FAO PLANT PRODUCTION AND PROTECTION PAPER 15 Sup.
Pesticide Residues In Food:
1977 Evaluations
The Monographs
Data And Recommendations
Of The Joint Meeting
Of The
FAO Panel Of Experts On Pesticide Residues And The Environment
And The
WHO Expert Group On Pesticide Residues,
Geneva, 6-15 December 1977
FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS
Rome 1978
The designations employed and the presentation of material in this
publication do not imply the expression of any opinion whatsoever on
the part of the Food and Agriculture Organization of the United
Nations concerning the legal status of any country, territory, city of
area or of its authorities, or concerning the delimitation of its
frontiers or boundaries.
M-84
ISBN 92-5-100828-0
The copyright in this book is vested in the Food and Agriculture
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should be addressed to the Director, Publications Division, Food and
Agriculture Organization of the United Nations, Via delle Terme di
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(C) FAO 1978
CONTENTS
List of Attendees
Introduction
The Monographs
(When the consideration of issues concerning a compound is fully
covered by a statement appearing in the Report of the Meeting the
present volume only provides a reference to the relevant section of
the Report).
Aldrin/dieldrin*
Amitrole*
Bromophos*
Bromophos-ethyl*
sec-Butylamine*
Captafol*
Captan*
Carbaryl*
Carbendazim*
Carbophenothion*
Chinomethionat*
Chlordane*
Chlordimeform (See Report section 4.13)
Chlorobenzilate*
Chlorothalonil*
Chlorpyrifos*
Cyhexatin (See Report section 4.17)
Daminozide
Dichlofluanid*
Dichlorvos*
Dicloran*
Dimethoata*
Diquat*
Dithiocarbamate fungicides*
Dodine*
Ethephon
Ethiofencarb
Fenamiphos*
Fenbutatin oxide
Fenitrothion*
Fenthion*
Heptachlor (See Report section 4.33)
Imazalil
Iprodione
Lindane*
Malathion*
Maleic hydrazide*
Methidathion (See Report section 4.39)
Methomyl*
Methoxychlor*
Phorate
Phosmet (See Corrigenda, p. 459)
Pirimiphos-methyl*
Propargite
Propineb
Propoxur (See Report section 4.46)
Quintozene*
Thiabendazole*
Thiophanate-methyl*
Triforin
Corrigenda to 1976 Evaluations
ANNEX 1 - Acceptable daily intakes for humans; residue limits and
guideline levels for compounds considered at the 1977 Joint Meeting.
*Addendum
1977 JOINT MEETING OF THE FAO PANEL OF EXPERTS ON PESTICIDE RESIDUES
AND ENVIRONMENT AND THE WHO EXPERT COMMITTEE ON PESTICIDE RESIDUES
Geneva, 6-15 December 1977
Members of the FAO Panel of Experts on Pesticide Residues and the
Environment
Dr. D.C. Abbott, Deputy Director (Customer Services), Laboratory of
the Government Chemist, Department of Industry, London, England
Dr. A.F.H. Besemer, Head, Pesticides Division, Plant Protection
Service, Ministry of Agriculture, and Agricultural University
(Phytopharmacy), Wageningen, Netherlands (Vice-chairman)
Professor G. Bressau, Head, Pesticides Unit, Division of Food
Chemistry, Federal Health Office, D 1000 Berlin 33 (West)
Mr. J.G. Cummings, Chief, Chemistry Branch, Registration Division,
Office of Pesticide Programmes, Environmental Protection Agency,
Washington, D.C., USA
Dr. E.D. Magallona, Assistant Professor and Head, Pesticide Residue
Laboratory, University of the Philippines at Los Baņos, College,
Laguna, Philippines
Mr. J.T. Snelson, Pesticides Coordinator, Department of Primary
Industry, Canberra, Australia (Rapporteur)
Observer Invited by FAO
Mr. A.J. Pieters, Chairman, Codex Committee on Pesticide Residues,
Directorate of Public Health, Foodstuffs Division, Leidschendam,
Netherlands
Members of the WHO Expert Committee on Pesticide Residues
Dr. W.F. Almeida, Director, Division of Animal Biology, Biological
Institute, Sao Paolo, Brazil
Mr. D.J. Clegg, Head, Pesticide Section, Toxicological Evaluation
Division, Foods Directorate Health Protection Branch, Department of
National Health and Welfare, Tunney's Pasture, Ottawa, K1A 0L2, Canada
(Chairman)
Professor F. Coulston, Director, Institute of Comparative and Human
Toxicology, Albany Medical College, Union University, Albany, N.Y.,
USA
Dr. M. van Logten, Head, Laboratory for General Toxicology, National
Institute of Public Health, Bilthoven, Netherlands
Professor E. Mahboubi, School of Public Health and Institute of Public
Health Research, University of Teheran, Teheran, Iran 1
Professor D.V. Parke, Chairman, Department of Biochemistry, University
of Surrey, Guildford, England (Rapporteur)
Secretariat
Dr. C. Agthe, Chief, Food Safety Unit, WHO, Geneva, Switzerland
Dr. L. Brader, Chief, Plant Protection Service, FAO, Rome, Italy
Dr. A. Hassan, Chemical Residue and Pollution Section, Joint FAO/IAEA
Division of Atomic Energy in Agriculture, Vienna, Austria
Dr. J.E. Huff, Unit of Chemical Carcinogenesis, International Agency
for Research on Cancer, Lyon, France
Dr. L. Ladomery, Food Standards Officer, Joint FAO/WHO Food Standards
Programme, FAO, Rome, Italy
Mr. A.F. Machin, Senior Research Officer, Central Veterinary
Laboratory, Ministry of Agriculture, Fisheries and Food, New Haw,
Weybridge, Surrey KT15 3NB, England (Consultant)
Dr. Orville E. Paynter, Department of Commerce, Office of
Environmental Affairs, Washington, D.C., USA (Temporary Advisor)
Mr. N. Saito, Plant Protection Service, FAO, Rome, Italy
Professor C. Schlatter, Institute of Toxicology, Federal Institute of
Technology and University of Zurich, CH-8603 Schwerzenbach/Zurich,
Switzerland (Temporary Advisor)
Dr E.E. Turtle, Pesticides Specialist, Plant Protection Service, FAO,
Rome, Italy (Joint Secretary)
Dr. G. Vettorazzi, Scientist, Food Safety Unit, WHO, Geneva,
Switzerland (Joint Secretary)
1 Present address: The Eppley Institute for Research in Cancer, The
University of Nebraska College of Medicine, Omaha, Nebraska, USA
INTRODUCTION
A Joint Meeting of the FAO Panel of Experts on Pesticide Residues and
the Environment and the WHO Expert Committee on Pesticide Residues was
held in Geneva from 6 to 15 December 1977. The report on the session
which is entitled "Report of the 1977 Joint Meeting of the FAO Panel
of Experts on Pesticide Residues and the Environment and the WHO
Expert Group on Pesticide Residues" provides information on the
general principles followed and considerations of the meeting. It also
contains a summary of the evaluations made on residues in foods of the
various pesticides considered at the session. The present document
contains summaries of the data considered by the Meeting together with
the recommendations made for acceptable daily intakes, for maximum
acceptable residue levels and for methods of analysis.
As much relevant information as possible has been included in the
monographs. This has been obtained from the published literature
wherever possible, but other sources of information have also been
used. Early and complete publications of the results of research in
this field are very important, particularly of these parts which can
form the basis for estimation of acceptable daily intakes and
appropriate residue levels. Publication allows the research to be
scrutinized and criticized by scientists from disciplines not
necessarily represented at the meeting. Data contained in unpublished
reports is less satisfactory and, when considered, must be complete
and nonconfidential and indicate authorship.
Some of the compounds considered at this meeting have been previously
evaluated and reported on in earlier publications. If only a limited
amount of additional information of these compounds has become
available at this meeting, only this latter information is summarized
in the pertinent monograph, and reference is made to the previously
published evaluation, which should also be consulted by the reader who
wishes to obtain a more complete evaluation of the compound. Such
monograph addenda are indicated by an asterisk in the "Contents"
sheet.
The Annex at the end of this volume of monographs is a slightly
corrected version of Annex I of the Report of the 1977 Joint Meeting
and it gives a Summary of the recommendations concerning acceptable
daily intakes, residue limits and guideline levels recommended at the
1977 Meeting.
NOTE TO THE READER
Any comments on evaluation for acceptable daily intake should be
addressed to:
Food Safety Unit
World Health Organization
Geneva, Switzerland
Any comments on residues in food and their evaluation should be
addressed to:
Plant Protection Service
Plant Production and Protection Division
Food and Agriculture Organization
Rome, Italy