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    PESTICIDE RESIDUES IN FOOD - 1982


    Sponsored jointly by FAO and WHO






    EVALUATIONS 1982





    Data and recommendations of the joint meeting
    of the FAO Panel of Experts on Pesticide Residues
    in Food and the Environment and the
    WHO Expert Group on Pesticide Residues
    Rome, 23 November - 2 December 1982

    Food and Agriculture Organization of the United Nations
    Rome 1983

    The designations employed and the presentation of material in this
    publication do not imply the expression of any opinion whatsoever on
    the part of the Food and Agriculture Organization of the United
    Nations concerning the legal status of any country, city or area or of
    its authorities, or concerning the delimitation of its frontiers or
    boundaries.

    M-84
    ISBN 92-5 101432-9

    All rights reserved.  No part of this publication may be reproduced,
    stored in a retrieval system, or transmitted in any form or by any
    means, electronic, mechanical, photocopying or otherwise, without the
    prior permission of the copyright owner.  Applications for such
    permission, with a statement of the purpose and extent of the
    reproduction, should be addressed to the Director, Publications
    Division, Food and Agriculture Organization of the United Nations, Via
    delle Terme di Caracalla, 00100 Rome, Italy.

    (c) FAO 1983

    CONTENTS

    List of Those Attending the Meeting

    Introduction

    The Monographs

         Acephate*
              WHO - Toxicology

         Aldicarb*
              WHO - Toxicology
              FAO - Residues

         Azocyclotin/Cyhexatin*
              FAO - Residues

         Bendiocarb
              WHO - Toxicology
              FAO - Residues

         Bromophos*
              FAO - Residues

         Captan*
              WHO - Toxicology

         Chlordane*
              WHO - Toxicology

         Chlorpyrifos*
              WHO - Toxicology
              FAO - Residues

         Cyanofenphos*
              FAO - Residues

         Cypermethrin*
              FAO - Residues

         Deltamethrin*
              WHO - Toxicology
              FAO - Residues

         Dichlofluanid*
              FAO - Residues

              

    *    Addendum

         Diphenylamine*
              WHO - Toxicology

         Endosulfan*
              WHO - Toxicology

         Ethiofencarb*
              WHO - Toxicology
              FAO - Residues

         Ethion*
              WHO - Toxicology

         Etrimfos*
              WHO - Toxicology

         Fenitrothion*
              WHO - Toxicology

         Fensulfothion*
              WHO - Toxicology

         Isofenphos*
              WHO - Toxicology
              FAO - Residues

         Metalaxyl
              WHO - Toxicology
              FAO - Residues

         Methacrifos*
              WHO - Toxicology

         Methamidophos*
              WHO - Toxicology

         Paraquat*
              WHO - Toxicology

         Parathion Methyl*
              WHO - Toxicology

         Permethrin*
              FAO - Residues

         Phorate*
              WHO - Toxicology

              

    *    Addendum

         Phosphamidon*
              WHO - Toxicology

         Phoxim
              WHO - Toxicology

         Pirimicarb*
              WHO - Toxicology

         Propargite*
              WHO - Toxicology
              FAO - Residues

         Triazophos
              WHO - Toxicology

         Vamidothion*
              WHO - Toxicology

         Annex I - Acceptable Daily Intakes, Maximum Residue Limits and
                   Guideline Levels Proposed at the 1982 Meeting

         Annex II - Previous FAO and WHO Documentation

              

    *    Addendum
    

    1982 JOINT MEETING OF THE FAO PANEL OF EXPERTS ON PESTICIDE RESIDUES
    IN FOOD AND THE ENVIRONMENT AND THE WHO EXPERT GROUP ON PESTICIDE
    RESIDUES

    Rome, 22 November - 1 December 1982

    FAO Panel of Experts on Pesticide Residues in Food and the Environment

    A. Ambrus, Plant Protection and Agrochemistry Centre, Budapest,
    Hungary

    J.A.R. Bates, Pesticide Registration Department, Ministry of
    Agriculture, Fisheries and Food, Hatching Green, Harpenden, Herts, UK
    (Rapporteur)

    K.R. Hill, Analytical Chemistry Laboratory, US Department of
    Agriculture, Agricultural Environment Quality Institute, Beltsville,
    Md, USA (Chairman)

    N.F. Ives, Office of Pesticide Programs, Environmental Protection
    Agency, Washington, DC, USA

    M.A. Martinez, Department of Pesticides, Dirección/General, Sanidad
    Vegetal, Mexico City, Mexico

    K. Voldum-Clausen, Division of Pesticides and Contaminants, National
    Food Institute, Soborg, Denmark

    Observer invited by FAO

    A.J. Pieters, Directorate of Public Health, Foodstuffs Division,
    Leidschendam, Netherlands (Chairman of the Codex Committee on
    Pesticide Residues)

    WHO Expert Group on Pesticide Residues

    C. Amerasekere, Department of Forensic Medicine, University of
    Peradeniya, Peradeniya, Sri Lanka

    D. Clegg, Pesticide Section, Toxicological Evaluation Division,
    National Health and Welfare, Ottawa, Canada (Vice-Chairman)

    D. de Paola, Department of Pathology, University Hospital, Rio de
    Janeiro, Brazil

    D.V. Parke, Department of Biochemistry, University of Surrey,
    Guildford, England

    O.E. Paynter, US Department of Commerce, Washington, DC, USA

    R. Plestina, Institute for Medical Research and Occupational Health,
    Zagreb, Yugoslavia

    FAO/WHO Secretariat

    A. Adam, Plant Protection Service, FAO, Rome, Italy (Secretary of the
    FAO Panel of Experts on Pesticide Residues in Food and the
    Environment)

    A.L. Black, Commonwealth Department of Health, Woden, Australia (WHO
    Temporary Adviser)

    J.R. Cabral, Unit of Chemical Carcinogenesis, International Agency for
    Research on Cancer, Lyon, France

    A. Di Muccio, Toxicological Laboratory, Instituto Superiore de Sanità,
    Rome, Italy (WHO Temporary Adviser)

    R.B. Jaeger, US Environmental Protection Agency, Washington, DC, USA
    (WHO Temporary Adviser)

    A.F. Machin, Central Veterinary Laboratory, Ministry of Agriculture,
    Fisheries and Food, Weybridge, Surrey, UK (FAO Consultant)

    T. Pekkanen, Department of Food Hygiene, College of Veterinary
    Medicine, Helsinki, Finland (WHO Temporary Adviser)

    R. Read, International Programme on Chemical Safety, Division of
    Environmental Health, WHO, Geneva, Switzerland

    A.G. Rico, Laboratoire de Radioélements et d'Etudes Métaboliques,
    Ecole Nationale Vétérinaire, Toulouse, France (WHO Temporary Adviser)

    M. Tobe, Division of Toxicology, Biological Research Centre, National
    Institute of Hygienic Sciences, Tokyo, Japan (WHO Temporary Adviser)

    G. Vettorazzi, International Programme on Chemical Safety, Division of
    Environmental Health, WHO, Geneva, Switzerland (Secretary of the WHO
    Expert Group on Pesticide Residues)

    E. Weisenberg, Institute for the Standardization and Control of
    Pharmaceuticals, Ministry of Health, Jerusalem, Israel (WHO Temporary
    Adviser)

    D. Wu-Lau, Pesticide Section, National Health and Welfare, Ottawa,
    Canada, (WHO Temporary Adviser)

    K. Zammarano, Plant Protection Service, FAO, Rome, Italy (Monographs
    Editor)

    INTRODUCTION

         The report of the Joint Meeting of the FAO Panel of Experts on
    Pesticide Residues in Food and the Environment and the WHO Expert
    Group on Pesticide Residues, held in Rome from 22 November - 1
    December 1982, contains a summary of the evaluations of residues in
    foods of the various pesticides considered at the session as well as
    information on the general principles followed by the Meeting. The
    present document contains summaries of the data considered, together
    with the recommendations made.

         The information included in the monographs has been obtained from
    the published literature wherever possible, but other sources have
    also been used. Early and complete publication of the results of
    research in this field are very important, particularly those data
    which can form the basis for the estimation of acceptable daily
    intakes and appropriate residue levels. Publication allows the
    research to be assessed by scientists from disciplines not necessarily
    represented at the meeting. Data contained in unpublished reports is
    less satisfactory and, when considered, must be complete and
    nonconfidential and indicate authorship.

         Some of the compounds considered at this Meeting have been
    previously evaluated and reported on in earlier publications. Only new
    information is summarized in the relevant monographs and reference is
    made to the previously published evaluation(s), which should also be
    consulted. Such monograph addenda are indicated by an asterisk in the
    "Contents" sheet.

         Annex 1 to this volume of monographs summarizes the
    recommendations on acceptable daily intakes, maximum residue limits
    and guideline levels made at the 1982 Meeting. It has already appeared
    as an annex to the report of the Meeting.

    NOTE

    Any comments on evaluation for acceptable daily intake should be
    addressed to:

    Food Safety Unit
    World Health Organization
    Geneva, Switzerland

    Any comments on residues in food and their evaluation should be
    addressed to:

    Pesticide Residues Specialist
    Plant Protection Service
    Plant Production and Protection Division
    Food and Agriculture Organization
    Rome, Italy





















    See Also:
       Toxicological Abbreviations