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    FAO PLANT PRODUCTION AND PROTECTION PAPER 15 Sup.





    Pesticide Residues In Food:
    1977 Evaluations





    The Monographs

    Data And Recommendations
    Of The Joint Meeting
    Of The
    FAO Panel Of Experts On Pesticide Residues And The Environment
    And The
    WHO Expert Group On Pesticide Residues,
    Geneva, 6-15 December 1977

    FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS
    Rome 1978

    The designations employed and the presentation of material in this
    publication do not imply the expression of any opinion whatsoever on
    the part of the Food and Agriculture Organization of the United
    Nations concerning the legal status of any country, territory, city of
    area or of its authorities, or concerning the delimitation of its
    frontiers or boundaries.

    M-84
    ISBN 92-5-100828-0

    The copyright in this book is vested in the Food and Agriculture
    Organization of the United Nations. The book may not be reproduced, in
    whole or in part, by any method or process, without written permission
    from the copyright holder. Applications for such permission, with the
    statement of the purpose and extent of the reproduction desired,
    should be addressed to the Director, Publications Division, Food and
    Agriculture Organization of the United Nations, Via delle Terme di
    Caracalla, 00100 Rome, Italy.

    (C) FAO 1978

    CONTENTS

    List of Attendees

    Introduction

    The Monographs

    (When the consideration of issues concerning a compound is fully
    covered by a statement appearing in the Report of the Meeting the
    present volume only provides a reference to the relevant section of
    the Report).

    Aldrin/dieldrin*

    Amitrole*

    Bromophos*

    Bromophos-ethyl*

    sec-Butylamine*

    Captafol*

    Captan*

    Carbaryl*

    Carbendazim*

    Carbophenothion*

    Chinomethionat*

    Chlordane*

    Chlordimeform (See Report section 4.13)

    Chlorobenzilate*

    Chlorothalonil*

    Chlorpyrifos*

    Cyhexatin (See Report section 4.17)

    Daminozide

    Dichlofluanid*

    Dichlorvos*

    Dicloran*

    Dimethoata*

    Diquat*

    Dithiocarbamate fungicides*

    Dodine*

    Ethephon

    Ethiofencarb

    Fenamiphos*

    Fenbutatin oxide

    Fenitrothion*

    Fenthion*

    Heptachlor (See Report section 4.33)

    Imazalil

    Iprodione

    Lindane*

    Malathion*

    Maleic hydrazide*

    Methidathion (See Report section 4.39)

    Methomyl*

    Methoxychlor*

    Phorate

    Phosmet (See Corrigenda, p. 459)

    Pirimiphos-methyl*

    Propargite

    Propineb

    Propoxur (See Report section 4.46)

    Quintozene*

    Thiabendazole*

    Thiophanate-methyl*

    Triforin

    Corrigenda to 1976 Evaluations

    ANNEX 1 - Acceptable daily intakes for humans; residue limits and
    guideline levels for compounds considered at the 1977 Joint Meeting.


                   

    *Addendum
    

    1977 JOINT MEETING OF THE FAO PANEL OF EXPERTS ON PESTICIDE RESIDUES
    AND ENVIRONMENT AND THE WHO EXPERT COMMITTEE ON PESTICIDE RESIDUES

    Geneva, 6-15 December 1977

    Members of the FAO Panel of Experts on Pesticide Residues and the
    Environment

    Dr. D.C. Abbott, Deputy Director (Customer Services), Laboratory of
    the Government Chemist, Department of Industry, London, England

    Dr. A.F.H. Besemer, Head, Pesticides Division, Plant Protection
    Service, Ministry of Agriculture, and Agricultural University
    (Phytopharmacy), Wageningen, Netherlands (Vice-chairman)

    Professor G. Bressau, Head, Pesticides Unit, Division of Food
    Chemistry, Federal Health Office, D 1000 Berlin 33 (West)

    Mr. J.G. Cummings, Chief, Chemistry Branch, Registration Division,
    Office of Pesticide Programmes, Environmental Protection Agency,
    Washington, D.C., USA

    Dr. E.D. Magallona, Assistant Professor and Head, Pesticide Residue
    Laboratory, University of the Philippines at Los Baņos, College,
    Laguna, Philippines

    Mr. J.T. Snelson, Pesticides Coordinator, Department of Primary
    Industry, Canberra, Australia (Rapporteur)

    Observer Invited by FAO

    Mr. A.J. Pieters, Chairman, Codex Committee on Pesticide Residues,
    Directorate of Public Health, Foodstuffs Division, Leidschendam,
    Netherlands

    Members of the WHO Expert Committee on Pesticide Residues

    Dr. W.F. Almeida, Director, Division of Animal Biology, Biological
    Institute, Sao Paolo, Brazil

    Mr. D.J. Clegg, Head, Pesticide Section, Toxicological Evaluation
    Division, Foods Directorate Health Protection Branch, Department of
    National Health and Welfare, Tunney's Pasture, Ottawa, K1A 0L2, Canada
    (Chairman)

    Professor F. Coulston, Director, Institute of Comparative and Human
    Toxicology, Albany Medical College, Union University, Albany, N.Y.,
    USA

    Dr. M. van Logten, Head, Laboratory for General Toxicology, National
    Institute of Public Health, Bilthoven, Netherlands

    Professor E. Mahboubi, School of Public Health and Institute of Public
    Health Research, University of Teheran, Teheran, Iran 1

    Professor D.V. Parke, Chairman, Department of Biochemistry, University
    of Surrey, Guildford, England (Rapporteur)

    Secretariat

    Dr. C. Agthe, Chief, Food Safety Unit, WHO, Geneva, Switzerland

    Dr. L. Brader, Chief, Plant Protection Service, FAO, Rome, Italy

    Dr. A. Hassan, Chemical Residue and Pollution Section, Joint FAO/IAEA
    Division of Atomic Energy in Agriculture, Vienna, Austria

    Dr. J.E. Huff, Unit of Chemical Carcinogenesis, International Agency
    for Research on Cancer, Lyon, France

    Dr. L. Ladomery, Food Standards Officer, Joint FAO/WHO Food Standards
    Programme, FAO, Rome, Italy

    Mr. A.F. Machin, Senior Research Officer, Central Veterinary
    Laboratory, Ministry of Agriculture, Fisheries and Food, New Haw,
    Weybridge, Surrey KT15 3NB, England (Consultant)

    Dr. Orville E. Paynter, Department of Commerce, Office of
    Environmental Affairs, Washington, D.C., USA (Temporary Advisor)

    Mr. N. Saito, Plant Protection Service, FAO, Rome, Italy

    Professor C. Schlatter, Institute of Toxicology, Federal Institute of
    Technology and University of Zurich, CH-8603 Schwerzenbach/Zurich,
    Switzerland (Temporary Advisor)

    Dr E.E. Turtle, Pesticides Specialist, Plant Protection Service, FAO,
    Rome, Italy (Joint Secretary)

    Dr. G. Vettorazzi, Scientist, Food Safety Unit, WHO, Geneva,
    Switzerland (Joint Secretary)

                   

    1 Present address: The Eppley Institute for Research in Cancer, The
    University of Nebraska College of Medicine, Omaha, Nebraska, USA

    INTRODUCTION

    A Joint Meeting of the FAO Panel of Experts on Pesticide Residues and
    the Environment and the WHO Expert Committee on Pesticide Residues was
    held in Geneva from 6 to 15 December 1977. The report on the session
    which is entitled "Report of the 1977 Joint Meeting of the FAO Panel
    of Experts on Pesticide Residues and the Environment and the WHO
    Expert Group on Pesticide Residues" provides information on the
    general principles followed and considerations of the meeting. It also
    contains a summary of the evaluations made on residues in foods of the
    various pesticides considered at the session. The present document
    contains summaries of the data considered by the Meeting together with
    the recommendations made for acceptable daily intakes, for maximum
    acceptable residue levels and for methods of analysis.

    As much relevant information as possible has been included in the
    monographs. This has been obtained from the published literature
    wherever possible, but other sources of information have also been
    used. Early and complete publications of the results of research in
    this field are very important, particularly of these parts which can
    form the basis for estimation of acceptable daily intakes and
    appropriate residue levels. Publication allows the research to be
    scrutinized and criticized by scientists from disciplines not
    necessarily represented at the meeting. Data contained in unpublished
    reports is less satisfactory and, when considered, must be complete
    and nonconfidential and indicate authorship.

    Some of the compounds considered at this meeting have been previously
    evaluated and reported on in earlier publications. If only a limited
    amount of additional information of these compounds has become
    available at this meeting, only this latter information is summarized
    in the pertinent monograph, and reference is made to the previously
    published evaluation, which should also be consulted by the reader who
    wishes to obtain a more complete evaluation of the compound. Such
    monograph addenda are indicated by an asterisk in the "Contents"
    sheet.

    The Annex at the end of this volume of monographs is a slightly
    corrected version of Annex I of the Report of the 1977 Joint Meeting
    and it gives a Summary of the recommendations concerning acceptable
    daily intakes, residue limits and guideline levels recommended at the
    1977 Meeting.

    NOTE TO THE READER

    Any comments on evaluation for acceptable daily intake should be
    addressed to:

    Food Safety Unit
    World Health Organization
    Geneva, Switzerland

    Any comments on residues in food and their evaluation should be
    addressed to:

    Plant Protection Service
    Plant Production and Protection Division
    Food and Agriculture Organization
    Rome, Italy





















    See Also:
       Toxicological Abbreviations