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HYDRAZINE
ICSC: 0281
Peer-Review Status: 25.11.2009 Validated
Diamide
Diamine
Nitrogen hydride
(anhydrous) 
CAS #: 302-01-2 RTECS #: MU7175000
UN #: 2029
EC #: 007-008-00-3
EINECS #: 206-114-9
    Formula: N2H4 / H2N-NH2
Molecular mass: 32.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Flammable.  NO open flames, NO sparks and NO smoking.  Use alcohol-resistant foam, foam, water spray, dry powder, carbon dioxide. 
EXPLOSION Above 40°C explosive vapour/air mixtures may be formed. Risk of fire and explosion on contact with many materials.  Above 40°C use a closed system, ventilation and explosion-proof electrical equipment.  In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position. 
 
EXPOSURE   AVOID ALL CONTACT!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Cough. Burning sensation. Headache. Confusion. Drowsiness. Nausea. Shortness of breath. Convulsions. Unconciousness.  Use closed system and ventilation.  Fresh air, rest. Half-upright position. Refer immediately for medical attention. 
Skin MAY BE ABSORBED! Redness. Pain. Skin burns.  Protective gloves. Protective clothing.  First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. See Notes. Refer immediately for medical attention. 
Eyes Redness. Pain. Blurred vision. Severe burns.  Wear face shield or eye protection in combination with breathing protection.  Rinse with plenty of water (remove contact lenses if easily possible). Refer immediately for medical attention. 
Ingestion Burns in mouth and throat. Abdominal pain. Diarrhoea. Vomiting. Shock or collapse. Further see Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Give nothing to drink. Do NOT induce vomiting. Refer immediately for medical attention. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable non-metallic containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT absorb in saw-dust or other combustible absorbents.  Special material.
Unbreakable packaging.
Put breakable packaging into closed unbreakable container.
Do not transport with food and feedstuffs. 
EC Classification
Symbol: T, N; R: 45-10-23/24/25-34-43-50/53; S: 53-45-60-61; Note: E 
UN Classification
UN Hazard Class: 8; UN Subsidiary Risks: 3 and 6.1; UN Pack Group: I 
GHS Classification
Signal: Danger
Flammable liquid and vapour
Fatal in contact with skin
Fatal if inhaled vapour
Toxic if swallowed
Causes severe skin burns and eye damage
May cause an allergic skin reaction
Suspected of causing genetic defects
Suspected of causing cancer
Causes damage to liver and central nervous system
Causes damage to the liver, the lungs, the kidneys and the central nervous system through prolonged or repeated exposure
Very toxic to aquatic life with long lasting effects 
flam;flamecorrskull;toxiccancer;health hazenviro;aqua

EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H4; F4; R3.  Fireproof. Separated from acids, metals, oxidants and food and feedstuffs. Keep under inert gas. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS FUMING OILY HYGROSCOPIC LIQUID WITH PUNGENT ODOUR. 

Physical dangers
No data. 

Chemical dangers
Decomposes . This produces ammonia, hydrogen and nitrogen oxides. This generates fire and explosion hazard. The substance is a strong reducing agent. It reacts violently with oxidants. The substance is a medium strong base. Reacts violently with acids, many metals, metal oxides and porous materials. This generates fire and explosion hazard. Air or oxygen is not required for decomposition. 

Occupational exposure limits
TLV: 0.01ppm as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2009).
MAK: Carcinogen category: 2; Skin absorption (H); Sensitization of skin (SH); (DFG 2009). 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. Serious local effects by all routes of exposure. 

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is corrosive to the eyes, skin and respiratory tract. Inhalation may cause lung oedema, but only after initial corrosive effects on eyes and/or airways have become manifest. Corrosive on ingestion. The substance may cause effects on the liver and central nervous system. Exposure could cause death. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the liver, kidneys and central nervous system. This substance is possibly carcinogenic to humans. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 114°C
Melting point: 2°C
Relative density (water = 1): 1.01
Solubility in water: miscible
Vapour pressure, kPa at 20°C: 2.1
Relative vapour density (air = 1): 1.1
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 40°C c.c.
Auto-ignition temperature: 270°C
Explosive limits, vol% in air: 4.7-100
Octanol/water partition coefficient as log Pow: -2.1
Viscosity: 0.0009 mm²/s at 20°C 
The substance is very toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment. 

NOTES
Auto-ignition temperature varies from 24°C on a rusty iron surface to 270°C on glass surface.
The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
The odour warning when the exposure limit value is exceeded is insufficient.
Rinse contaminated clothing with plenty of water because of fire hazard.
Do NOT take working clothes home.
Other UN numbers are: UN 2030 Hydrazine aqueous solution, with more than 37% hydrazine by mass, having a flash-point of not more than 60 °C: hazard class: 8, subsdiary risks: 3 and/or 6.1, packing group: I; Hydrazine aqueous solution, with more than 37% hydrazine by mass: hazard class: 8, subsdiary risk: 6.1, packing group: II-III. UN 3293 Hydrazine, aqueous solutions with not more than 37% of hydrazine, hazard class: 6.1, packing group: III. Other CAS-numbers are: 7803-57-8 for the 64% aqueous solution and 10217-52-4 for the 55% aqueous solution. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.
    See Also:
       Toxicological Abbreviations
       Hydrazine (EHC 68, 1987)
       Hydrazine (HSG 56, 1991)
       Hydrazine (IARC Summary & Evaluation, Volume 71, 1999)