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    WHO Pesticide Residues Series. No. 2

    1972 EVALUATIONS OF SOME PESTICIDE RESIDUES IN FOOD

    THE MONOGRAPHS

    The evaluations contained in these monographs were prepared by the
    Joint Meeting of the FAO Working Party of Experts on Pesticide
    Residues and the WHO Expert Committee on Pesticide Residues that met
    in Rome from 20 to 28 November 1972.1

    World Health Organization
    Geneva
    1973

              

    1  Pesticide Residues in Food: Report of the 1972 Joint Meeting of
    the FAO Working Party of Experts on Pesticide Residues and the WHO
    Expert Committee on Pesticide Residues, Wld Hlth Org. techn. Rep.
    Ser., 1973, No. 525; FAO Agricultural Studies, 1973, No. 90.

    These monographs are also issued by the Food and Agriculture
    Organization of the United Nations, Rome, as document AGP:1972/M/9/1.

    (c) FAO and WHO 1973

    CONTENTS

    List of Attendees

    Introduction

    The Monographs

    Azinphos-methyl

    Bromophos

    Bromophos-ethyl

    Carbophenothion

    Chlordane*

    Chlormequat*

    Chlorobenzilate*

    Chloropropylate*

    Chlorpyrifos

    Coumaphos*

    Crufomate*

    Dioxathion*

    Diquat*

    Ethion*

    Fenchlorphes*

    Fensulfothion

    Fentin Compounds*

    Formothion*

    Methidathion

    Mevinphos*

    Monocrotophos

    Paraquat*

    Parathion-methyl*


    Phosalone

    Phosphamidon*

    Piperonyl butoxide*

    Pyrethrins*

    Thiabendazole

    Annex 1 - Index to documentation and summary of recommendations
    concerning acceptable daily intakes, tolerances, and practical residue
    limits, as of December 1972

    ANNEX 2 - References

              

    * Addendum
    

    LIST OF ATTENDEES

    Members of the FAO Working Party of Experts on Pesticide Residues:

    Dr. D.C. Abbott, Senior Superintendent, Environmental Chemistry,
    Laboratory of the Government Chemist, Department of Trade and
    Industry, London, England

    Dr. A.F.H. Besemer, Head, Pesticides Division, Plant Protection
    Service, Ministry of Agriculture, Wageningen, Netherlands

    Dr. K. Glogowski, Deputy Director (Scientific), Plant Protection
    Institute, Posnan, Poland

    Dr. K.R. Hill, US Department of Agriculture, Analytical Chemistry
    Laboratory, Agricultural Environmental Quality Institute - ARS,
    Beltsville, Md., USA (Chairman)

    Dr. P.E. Koivistoinen, Director, Institute of Food Chemistry and
    Technology, University of Helsinki, Finland

    Mr. J.T. Snelson, Pesticides Co-ordinator, Department of Primary
    Industry, Canberra, Australia (Rapporteur)

    Members of the WHO Expert Committee on Pesticide Residues:

    Dr. W.F. Almeida, Director, Division of Animal Biology, Biological
    Institute, Sao Paulo, Brazil

    Dr. V. Benes, Chief, Division of Toxicology and Reference Laboratory,
    Institute of Hygiene and Epidemiology, Prague, Czechoslovakia

    Mr. D.J. Clegg, Head, Pesticide Unit, Division of Toxicology, Food
    Advisory Bureau, Health Protection Branch, Ottawa, Ontario, Canada
    (Rapporteur)

    Dr. S.D. Murphy, Associate Professor of Toxicology, Harvard
    University, School of Public Health, Boston, Mass., USA

    Professor I. Nir, Head, Department of Clinical Pharmacology, Ministry
    of Health, Jerusalem, Israel

    Dr. H.G. Verschuuren, Head, Department of Biological Toxicology of
    Pesticides, National Institute of Public Health, Bilthoven,
    Netherlands (Vice-Chairman)

    Secretariat:

    Dr. R.L. Baron, Environmental Protection Agency, Perrine Primate
    Laboratory, Perrine, Fla., USA (Consultant)

    Dr. L. Ladomery, Food Standards Officer, Food Standards Branch
    (FAO/WHO Programme) International Agency Liaison Division, FAO, Rome,
    Italy

    Dr. F.C. Lu, Chief Scientist, Food Additives, WHO, Geneva, Switzerland
    (Joint Secretary)

    Dr. H. Marchart, Pesticide Residue and Pollution Section, Joint
    FAO/IAEA Division of Atomic Energy in Agriculture, Vienna, Austria

    Dr. M. Sharratt, Senior Medical Officer, Department of Health and
    Social Security, London, England (Consultant)

    Mrs. K. Tedesco-Zammarano, Plant Protection Service, FAO, Rome, Italy

    Dr. L. Tomatis, Chief Chemical Carcinogenesis Unit, International
    Agency for Research on Cancer, Lyon, France

    Dr. E.E. Turtle, Pesticides Specialist, Plant Protection Service, FAO,
    Rome, Italy (Joint Secretary)

    Dr. G. Vettorazzi, Scientist, Food Additives, WHO, Geneva, Switzerland

    INTRODUCTION

    A Joint Meeting of the FAO Working Party of Experts on Pesticide
    Residues and the WHO Expert Committee on Pesticide Residues was held
    in Rome in November, 1972. The general considerations, including the
    principles adopted for the evaluations and a summary of the results of
    evaluations on a number of pesticide residues, appear in the
    publication, "Report of the 1972 Joint Meeting of the FAO Working
    Party of Experts on Pesticide Residues and the WHO Expert Committee on
    Pesticide Residues".2 Additional information, including previously
    unpublished summaries of data considered by the Joint Meeting in
    arriving at recommendations for acceptable daily intakes, tolerances
    and methods of analysis, is to be found in this document.

    Many of the compounds considered at this meeting have been previously
    evaluated in earlier publications. If only a limited amount of
    additional information on these compounds has become available in the
    intervening years, only this latter information is summarized in the
    pertinent monograph, and reference is made to the previously published
    evaluation, which should also be consulted by the reader who wishes to
    obtain a complete evaluation of the compound. Such monograph addenda
    are indicated by an asterisk in the "Contents", p. iii. If a large
    amount of data has become available since the previously published
    evaluation, or if the compound was first considered by the Joint
    Meeting in 1972, the pertinent monograph is reproduced in its
    entirety.

    As much relevant information as possible has been included in the
    monographs. This has been obtained from the published literature
    wherever possible, but other sources of information have also been
    used. Early and complete publication of the results of research in
    this field is very important, particularly of that part which could
    form the basis for estimation of acceptable daily intakes and
    appropriate tolerances.

    Publication allows the research to be scrutinized and criticized by
    scientists from disciplines not necessarily represented at the
    meeting. Data contained in unpublished reports, because they may
    include more detail than published work, are often acceptable.
    However, such reports must be complete and nonconfidential and
    indicate authorship.


              

    2 Pesticide residues in food. Report of the 1972 Joint Meeting of the
    FAO Working Party of Experts on Pesticide Residues and the WHO Expert
    Committee on Pesticide Residues, WHO Technical Report Series No. 525,
    FAO Agricultural Studies, No. 90.

    Two appendices have been included at the end of this series of
    monographs. Appendix I is a reproduction of Appendix I in the Report
    of the 1972 Joint Meeting,3 and gives the source of all the previous
    monographs of various compounds. Appendix II gives bibliographic data
    of a general nature.


    NOTE TO THE READER

    Any comments on residues in food and their evaluation should be
    addressed to:

         Plant Protection Service
         Plant Production and Protection Division
         Food and Agriculture Organization
         Rome, Italy

    Any comments on evaluation for acceptable daily intakes should be
    addressed to:

         Food Additives Unit
         World Health Organization
         Geneva, Switzerland

              

    3 Pesticide residues in food. Report of the 1972 Joint Meeting of the
    FAO Working Party of Experts on Pesticide Residues and the WHO Expert
    Committee on Pesticide Residues, WHO Technical Report Series, No. 525,
    FAO Agricultural Studies, No. 90.






















    See Also:
       Toxicological Abbreviations