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NITROFEN
ICSC: 0929
Peer-Review Status: 24.03.1999 Validated
2,4-Dichloro-1-(4-nitrophenoxy) benzene
2,4-Dichlorophenyl p-nitrophenyl ether 
CAS #: 1836-75-5 RTECS #: KN8400000
EC #: 609-040-00-9
EINECS #: 217-406-0
    Formula: C12H7Cl2NO3 / C6H3Cl2OC6H4NO2
Molecular mass: 284.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible.  NO open flames.  Use water spray, powder, foam, carbon dioxide. 
EXPLOSION Finely dispersed particles form explosive mixtures in air.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent deposition of dust.   
 
EXPOSURE   PREVENT DISPERSION OF DUST! AVOID ALL CONTACT! AVOID EXPOSURE OF (PREGNANT) WOMEN!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Abdominal pain. Cough. Diarrhoea. Dizziness. Headache. Laboured breathing. Sore throat. Vomiting.  Use local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. 
Skin Redness. Pain.  Protective gloves. Protective clothing.  First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Refer for medical attention . 
Eyes Redness. Pain.  Wear safety spectacles or eye protection in combination with breathing protection if powder.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Rest. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Sweep spilled substance into covered containers. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. Personal protection: P3 filter respirator for toxic particles.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T, N; R: 45-61-22-50/53; S: 53-45-60-61; Note: E 
UN Classification
 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
  Separated from food and feedstuffs. Well closed. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS-TO-BROWN CRYSTALLINE POWDER. TURNS DARK ON EXPOSURE TO LIGHT. 

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air. 

Chemical dangers
On combustion, forms toxic fumes. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):. 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered. 

Effects of short-term exposure
The substance is irritating to the skin and respiratory tract. The substance may cause effects on the central nervous system. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the liver. This substance is possibly carcinogenic to humans. Animal tests show that this substance possibly causes malformations in human babies. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point at 101.3kPa: 368°C
Melting point: 70-71°C
Density: 1.3 g/cm³
Solubility in water, g/100ml at 22°C: 0.0001
Vapour pressure, Pa at 40°C: 0.001
Flash point: >200°C c.c.
Auto-ignition temperature: >400°C
Octanol/water partition coefficient as log Pow: 3.4/5  
The substance is very toxic to aquatic organisms. Bioaccumulation of this chemical may occur in fish. The substance may cause long-term effects in the aquatic environment. Avoid release to the environment in circumstances different to normal use. 

NOTES
If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s).
Carrier solvents used in commercial formulations may change physical and toxicological properties.
Do NOT take working clothes home.
Tok-2, Tok E25, Tokkorn, Mezotox, FW925, Niclofen, NIP, Nitrochlor, Trazalex are trade names. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Nitrofen (Pesticide residues in food: 1983 evaluations)
       Nitrofen (IARC Summary & Evaluation, Volume 30, 1983)