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GLYPHOSATE
ICSC: 0160
Peer-Review Status: 19.04.2005 Validated
N-(Phosphonomethyl)glycine 
CAS #: 1071-83-6 RTECS #: MC1075000
EC #: 607-315-00-8
EINECS #: 213-997-4
    Formula: C3H8NO5P / HOOCCH2NHCH2PO(OH)2
Molecular mass: 169.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking.  Use water spray, powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION Finely dispersed particles form explosive mixtures in air.  Prevent build-up of electrostatic charges (e.g., by grounding). Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent deposition of dust.   
 
EXPOSURE   PREVENT DISPERSION OF DUST!   
Inhalation Cough.  Avoid inhalation of dust and mist.  Fresh air, rest. 
Skin Redness.  Protective gloves.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes Redness. Pain.  Wear safety goggles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Burning sensation in the throat and chest.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Do NOT induce vomiting. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered plastic containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: Xi, N; R: 41-51/53; S: (2)-26-39-61 
UN Classification
 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
  Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Well closed. Do NOT store or transport in containers made from galvanized steel or unlined steel. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS CRYSTALS. 

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air. If dry, it can be charged electrostatically by swirling, pneumatic transport, pouring, etc. 

Chemical dangers
Decomposes on heating. This produces toxic fumes including nitrogen oxides and phosphorus oxides. Attacks iron and galvanized steel. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):. 

Routes of exposure
 

Inhalation risk
A harmful concentration of airborne particles can be reached quickly on spraying. 

Effects of short-term exposure
The substance is severely irritating to the eyes. The substance is mildly irritating to the skin. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Decomposes at <234°C
Density: 1.7 g/cm³
Solubility in water, g/100ml at 25°C: 1.2
Vapour pressure at 20°C: negligible
Octanol/water partition coefficient as log Pow: -1.0  
The substance is toxic to aquatic organisms. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
Sodium, potassium and amine salts are readily soluble in water.
Roundup (for the monoisopropyl ammonium salt) and Polado (for the sesquisodium salt) are trade names.
Carrier solvents used in commercial formulations may change physical and toxicological properties. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Glyphosate (EHC 159, 1994)
       Glyphosate (Pesticide residues in food: 1986 evaluations Part II Toxicology)