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ACRYLONITRILE
ICSC: 0092
Peer-Review Status: 13.03.2001 Validated
Cyanoethylene
2-Propenenitrile
Vinyl cyanide 
CAS #: 107-13-1 RTECS #: AT5250000
UN #: 1093
EC #: 608-003-00-4
EINECS #: 203-466-5
    Formula: C3H3N / CH2=CH-CN
Molecular mass: 53.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking. NO contact with strong bases or strong acids.  Use water spray, powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION Vapour/air mixtures are explosive. Risk of fire and explosion on contact with strong bases or strong acids.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Use non-sparking handtools.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   AVOID ALL CONTACT!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Dizziness. Headache. Nausea. Shortness of breath. Vomiting. Weakness. Convulsions. Chest tightness.  Use closed system or ventilation.  Fresh air, rest. Refer for medical attention. See Notes. 
Skin MAY BE ABSORBED! Redness. Pain. Blisters. Further see Inhalation.  Protective gloves. Protective clothing.  First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Refer for medical attention . 
Eyes Redness. Pain.  Wear safety goggles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Vomiting. Further see Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Give a slurry of activated charcoal in water to drink. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Personal protection: chemical protection suit including self-contained breathing apparatus. Ventilation. Do NOT wash away into sewer. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in covered containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Unbreakable packaging.
Put breakable packaging into closed unbreakable container.
Do not transport with food and feedstuffs. 
EC Classification
Symbol: F, T, N; R: 45-11-23/24/25-37/38-41-43-51/53; S: 9-16-53-45-61; Note: D, E 
UN Classification
UN Hazard Class: 3; UN Subsidiary Risks: 6.1; UN Pack Group: I 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-30S1093.
NFPA Code: H4; F3; R2. 
Fireproof. Separated from strong oxidants, strong bases and food and feedstuffs. Cool. Keep in the dark. Ventilation along the floor. Store only if stabilized. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS OR PALE YELLOW LIQUID WITH PUNGENT ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. 

Chemical dangers
The substance polymerizes due to heating and under the influence of light and bases. This generates fire or explosion hazard. Decomposes on heating. This produces toxic fumes including hydrogen cyanide and nitrogen oxides. Reacts violently with strong acids and strong oxidants. Attacks plastics and rubber. 

Occupational exposure limits
TLV: 2ppm as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2004).
MAK: Carcinogen category: 2; Skin absorption (H); Sensitization of skin (SH); (DFG 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance and the vapour are irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system. Exposure far above the OEL could cause death. The effects may be delayed. See Notes. Medical observation is indicated. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the central nervous system and liver. This substance is possibly carcinogenic to humans. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 77°C
Melting point: -84°C
Relative density (water = 1): 0.8
Solubility in water, g/100ml at 20°C: 7
Vapour pressure, kPa at 20°C: 11.0
Relative vapour density (air = 1): 1.8
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.05
Flash point: -1°C c.c.
Auto-ignition temperature: 481°C
Explosive limits, vol% in air: 3.0-17.0
Octanol/water partition coefficient as log Pow: 0.25  
The substance is harmful to aquatic organisms. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Exposure to the substance will result in cyanide formation.
Also consult ICSC of a cyanide salt, such as 0671.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
The odour warning when the exposure limit value is exceeded is insufficient.
Rinse contaminated clothes (fire hazard) with plenty of water.
Card has been partly updated in April 2005.
See section Occupational Exposure Limits. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Acrylonitrile (EHC 28, 1983)
       Acrylonitrile (HSG 1, 1986)
       Acrylonitrile (WHO Food Additives Series 19)
       ACRYLONITRILE (JECFA Evaluation)
       Acrylonitrile (FAO Meeting Report PL/1965/10/2)
       Acrylonitrile (CICADS 39, 2002)
       Acrylonitrile (IARC Summary & Evaluation, Volume 71, 1999)