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ACETONEICSC: 0087
April 2009
CAS #: 67-64-12-Propanone
Dimethyl ketone
Methyl ketone
UN #: 1090
EINECS #: 200-662-2

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Highly flammable.  Vapour/air mixtures are explosive. Heating will cause rise in pressure with risk of bursting.  NO open flames, NO sparks and NO smoking.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling. Use non-sparking handtools.  Use powder, alcohol-resistant foam, water, carbon dioxide.  In case of fire: keep drums, etc., cool by spraying with water. 

   
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation Sore throat. Cough. Confusion. Headache. Dizziness. Drowsiness. Unconsciousness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Dry skin.  Protective gloves.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness. Pain. Blurred vision.  Wear safety spectacles.  Rinse with plenty of water (remove contact lenses if easily possible). Refer for medical attention. 
Ingestion Nausea. Vomiting. Further see Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Remove all ignition sources. Personal protection: filter respirator for organic gases and vapours of low boiling point adapted to the airborne concentration of the substance. Ventilation. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer. 

According to UN GHS Criteria

flam;flame
DANGER
Highly flammable liquid and vapour
Causes eye irritation 

Transportation
UN Classification
UN Hazard Class: 3; UN Pack Group: II 

STORAGE
Fireproof. Separated from : see Chemical Dangers. Store in an area without drain or sewer access. 
PACKAGING
 
ACETONE ICSC: 0087
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. 

Chemical dangers
Contact with strong oxidants such as acetic acid, nitric acid and hydrogen peroxide generates explosive peroxides. Reacts with chloroform and bromoform under basic conditions. This generates fire and explosion hazard. Attacks plastics. 

Formula: C3H6O / CH3-CO-CH3
Molecular mass: 58.1
Boiling point: 56°C
Melting point: -95°C
Relative density (water = 1): 0.8
Solubility in water: miscible
Vapour pressure, kPa at 20°C: 24
Relative vapour density (air = 1): 2.0
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.2
Flash point: -18°C c.c.
Auto-ignition temperature: 465°C
Explosive limits, vol% in air: 2.2-13
Octanol/water partition coefficient as log Pow: -0.24
Viscosity: 0.34 mm²/s at 40°C 


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation. 

Effects of short-term exposure
The substance is irritating to the eyes and respiratory tract. Exposure at high levels could cause lowering of consciousness. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C , on spraying or dispersing much faster. 

Effects of long-term or repeated exposure
The substance defats the skin, which may cause dryness or cracking. Repeated or prolonged contact with skin may cause dryness and cracking. 


Occupational exposure limits
TLV: 250 ppm as TWA; 500 ppm as STEL; BEI issued; A4 (not classifiable as a human carcinogen).
MAK: 1200 mg/m3, 500 ppm; peak limitation category: I(2); pregnancy risk group: B.
EU-OEL: 1210 mg/m3, 500 ppm as TWA 

ENVIRONMENT
 

NOTES
Use of alcoholic beverages enhances the harmful effect. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: F, Xi; R: 11-36-66-67; S: (2)-9-16-26 

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    See Also:
       Toxicological Abbreviations
       Acetone (EHC 207, 1998)
       Acetone (FAO Nutrition Meetings Report Series 48a)
       ACETONE (JECFA Evaluation)
       Acetone  (SIDS)