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ACETONE
ICSC: 0087
Peer-Review Status: 01.04.2009 Validated
2-Propanone
Dimethyl ketone
Methyl ketone 
CAS #: 67-64-1 RTECS #: AL3150000
UN #: 1090
EC #: 606-001-00-8
EINECS #: 200-662-2
    Formula: C3H6O / CH3-CO-CH3
Molecular mass: 58.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Highly flammable.  NO open flames, NO sparks and NO smoking.  Use powder, alcohol-resistant foam, water, carbon dioxide. 
EXPLOSION Vapour/air mixtures are explosive. Heating will cause rise in pressure with risk of bursting.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling. Use non-sparking handtools.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE      
Inhalation Sore throat. Cough. Confusion. Headache. Dizziness. Drowsiness. Unconciousness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Dry skin.  Protective gloves.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness. Pain. Blurred vision.  Wear safety spectacles.  Rinse with plenty of water (remove contact lenses if easily possible). Refer for medical attention. 
Ingestion Nausea. Vomiting. Further see Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Remove all ignition sources. Personal protection: filter respirator for organic gases and vapours of low boiling point adapted to the airborne concentration of the substance. Ventilation. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer.   
EC Classification
Symbol: F, Xi; R: 11-36-66-67; S: (2)-9-16-26-46 
UN Classification
UN Hazard Class: 3; UN Pack Group: II 
GHS Classification
Signal: Danger
Highly flammable liquid and vapour
Causes eye irritation 
flam;flame

EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H1; F3; R0.  Fireproof. Separated from : see Chemical Dangers. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. 

Chemical dangers
Contact with strong oxidants such as acetic acid, nitric acid and hydrogen peroxide generates explosive peroxides. Reacts with chloroform and bromoform under basic conditions. This generates fire and explosion hazard. Attacks plastics. 

Occupational exposure limits
TLV: 500 ppm as TWA; 750 ppm as STEL; A4 (not classifiable as a human carcinogen); BEI issued; (ACGIH 2009).
EU OEL ( selected): 500ppm, 1210mg/m³ as TWA; SCOEL recommendation available. 

Routes of exposure
The substance can be absorbed into the body by inhalation. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C ; on spraying or dispersing much faster. 

Effects of short-term exposure
The substance is irritating to the eyes and respiratory tract. Exposure at high levels could cause lowering of consciousness. 

Effects of long-term or repeated exposure
The liquid defats the skin. Repeated or prolonged contact with skin may cause dryness and cracking. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 56°C
Melting point: -95°C
Relative density (water = 1): 0.8
Solubility in water: miscible
Vapour pressure, kPa at 20°C: 24
Relative vapour density (air = 1): 2.0
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.2
Flash point: -18°C c.c.
Auto-ignition temperature: 465°C
Explosive limits, vol% in air: 2.2-13
Octanol/water partition coefficient as log Pow: -0.24
Viscosity: 0.34 mm²/s at 40°C 
 

NOTES
Use of alcoholic beverages enhances the harmful effect. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.
    See Also:
       Toxicological Abbreviations
       Acetone (EHC 207, 1998)
       Acetone (FAO Nutrition Meetings Report Series 48a)
       ACETONE (JECFA Evaluation)
       Acetone  (SIDS)