IPCS INCHEM Home
ARSENIC
ICSC: 0013
Peer-Review Status: 09.06.2011 Validated
Grey arsenic 
CAS #: 7440-38-2 RTECS #: CG0525000
UN #: 1558
EC #: 033-001-00-X
EINECS #: 231-148-6
    Formula: As
Atomic mass: 74.9

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames. NO contact with strong oxidizing agents. NO contact with hot surfaces.  Use water spray, powder, foam, carbon dioxide. 
EXPLOSION Risk of fire and explosion on contact with . See Chemical Dangers.  NO contact with incompatible materials: See Notes.   
 
EXPOSURE   PREVENT DISPERSION OF DUST! AVOID ALL CONTACT!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation See Ingestion.  Use closed system and ventilation.  Fresh air, rest. Seek medical attention if you feel unwell. 
Skin   Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes   Wear face shield or eye protection in combination with breathing protection if powder.  Rinse with plenty of water (remove contact lenses if easily possible). 
Ingestion Abdominal pain. Diarrhoea. Nausea. Vomiting. Weakness. Shock or collapse. Unconsciousness.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Refer immediately for medical attention. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T, N; R: 23/25-50/53; S: (1/2)-20/21-28-45-60-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 
GHS Classification
Signal: Danger
Toxic if swallowed
May cause cancer
Suspected of damaging fertility or the unborn child
Causes damage to the gastrointestinal tract if swallowed
Causes damage to organs through prolonged or repeated exposure
Toxic to aquatic life with long lasting effects 
skull;toxiccancer;health hazenviro;aqua

EMERGENCY RESPONSE SAFE STORAGE
  Separated from strong oxidants, acids, halogens and food and feedstuffs. Well closed. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
BRITTLE GREY METALLIC-LOOKING CRYSTALS. 

Physical dangers
No data. 

Chemical dangers
Upon heating, toxic fumes are formed. Reacts violently with strong oxidants and halogens. This generates fire and explosion hazard. Reacts with reducing agents. This produces toxic and flammable arsine gas (See ICSC 0222). 

Occupational exposure limits
TLV: 0.01mg/m³ as TWA; A1 (confirmed human carcinogen); BEI issued; (ACGIH 2010).
MAK: Carcinogen category: 1; Germ cell mutagen group: 3A; (DFG 2009). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. 

Inhalation risk
A harmful concentration of airborne particles can be reached quickly when dispersed, especially if powdered. 

Effects of short-term exposure
The substance may cause effects on the gastrointestinal tract. This may result in severe gastroenteritis, loss of fluids and electrolytes, cardiac disorders, shock and convulsions. Exposure far above the OEL could cause death. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
The substance may have effects on the skin, mucous membranes, peripheral nervous system, liver and bone marrow. This may result in pigmentation disorders, hyperkeratosis, perforation of the nasal septum, neuropathy, anaemia and liver impairment. This substance is carcinogenic to humans. Animal tests show that this substance possibly causes toxicity to human reproduction or development. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Sublimation point: 613°C
Density: 5.7 g/cm³
Solubility in water: none
Auto-ignition temperature: 180°C  
The substance is toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment. 

NOTES
The substance is combustible but no flash point is available in literature.
Depending on the degree of exposure, periodic medical examination is suggested.
Do NOT take working clothes home. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.
    See Also:
       Toxicological Abbreviations
       Arsenic (EHC 18, 1981)
       Arsenic (WHO Food Additives Series 18)
       Arsenic (WHO Food Additives Series 24)
       ARSENIC (JECFA Evaluation)
       Arsenic (PIM G042)