|DIMETHYL SULFATE||ICSC: 0148 (November 2008)|
|Sulfuric acid dimethyl ester
| CAS #: 77-78-1
| UN #: 1595
|EC Number: 201-058-1
|ACUTE HAZARDS||PREVENTION||FIRE FIGHTING|
|FIRE & EXPLOSION||Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Above 83°C explosive vapour/air mixtures may be formed.||NO open flames. Above 83°C use a closed system and ventilation.||Use powder, foam, carbon dioxide, water spray.|
|AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR!|
|Inhalation||Cough. Sore throat. Burning sensation. Shortness of breath. Headache. Symptoms may be delayed. See Notes.||Use ventilation, local exhaust or breathing protection.||Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer immediately for medical attention.|
|Skin||MAY BE ABSORBED! Redness. Pain. Blisters. Skin burns.||Protective gloves. Protective clothing.||Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer immediately for medical attention.|
|Eyes||Redness. Pain. Burns. Permanent loss of vision.||Wear face shield or eye protection in combination with breathing protection.||Rinse with plenty of water (remove contact lenses if easily possible). Refer immediately for medical attention.|
|Ingestion||Burns in mouth and throat. Burning sensation in the throat and chest. Abdominal cramps. Vomiting. Convulsions. Shock or collapse. Further see Inhalation.||Do not eat, drink, or smoke during work. Wash hands before eating.||Rinse mouth. Give one or two glasses of water to drink. Do NOT induce vomiting. Refer immediately for medical attention.|
|SPILLAGE DISPOSAL||CLASSIFICATION & LABELLING|
|Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Ventilation. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers. Absorb remaining liquid in dry sand or inert absorbent. Then store and dispose of according to local regulations.||
According to UN GHS Criteria
Fatal if inhaled
Toxic if swallowed
Causes severe skin burns and eye damage
May cause allergic skin reaction
Suspected of causing genetic defects
May cause cancer
Causes damage to liver, kidneys and lungs
Causes damage to the lungs through prolonged or repeated exposure
Harmful to aquatic life
|Separated from food and feedstuffs and incompatible materials. See Chemical Dangers. Cool. Dry. Well closed. Ventilation along the floor. Store in an area without drain or sewer access.|
Put breakable packaging into closed unbreakable container.
Do not transport with food and feedstuffs.
|DIMETHYL SULFATE||ICSC: 0148|
|PHYSICAL & CHEMICAL INFORMATION|
Physical State; Appearance
Formula: C2H6O4S / (CH3O)2SO2
|EXPOSURE & HEALTH EFFECTS|
Routes of exposure
Effects of short-term exposure
Effects of long-term or repeated exposure
|OCCUPATIONAL EXPOSURE LIMITS|
TLV: 0.1 ppm as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans).
MAK: skin absorption (H); carcinogen category: 2
|The substance is harmful to aquatic organisms.|
|Commercial dimethyl sulfate may contain trace amounts of sulfuric acid.
Depending on the degree of exposure, periodic medical examination is suggested.
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential.
Immediate administration of an appropriate inhalation therapy by a doctor, or by an authorized person, should be considered.
There is no odour warning even when toxic concentrations are present.
Do NOT take working clothes home.
Symbol: T+; R: 45-25-26-34-43-68; S: 53-45; Note: E
|All rights reserved. The published material is being distributed without warranty of any kind, either expressed or implied. Neither ILO nor WHO nor the European Commission shall be responsible for the interpretation and use of the information contained in this material.|
See Also: Toxicological Abbreviations Dimethyl sulfate (EHC 48, 1985) Dimethyl sulfate (HSG 29, 1989) Dimethyl Sulfate (IARC Summary & Evaluation, Volume 71, 1999)