IPCS INCHEM Home


    ANNEX II

    ACCEPTABLE DAILY INTAKES AND RESIDUE LIMITS PROPOSED AT THE
    1988 MEETING

         These figures are additional to, or amend, those recorded in
    Annexes to the reports of earlier meetings. Limits recommended at
    meetings from 1965 to 1977 inclusive are summarized in document
    FAO/WHO 1978c.

         The table includes maximum ADIs (acceptable daily intakes), and
    proposals for MRLs (maximum residue limits), including one ERL
    (extraneous residue limit) (for bromide ion). These terms are defined
    in Annex III of the report of the 1975 meeting.

         Some ADIs are temporary: this is indicated by the year when
    toxicological re-evaluation of the compound is scheduled in
    parenthesis below the ADI.

         All MRLs for compounds with temporary ADIs are necessarily
    temporary. MRLs may also be temporary, irrespective of the status of
    the ADI, because additional information is required for the evaluation
    of residues. These are followed by the qualification (T).

         If an MRL is an amendment, the previous value is also recorded,
    together with the year in which the level was estimated. The absence
    of a figure in the "Previous" column indicates that the recommendation
    is the first for the commodity or group concerned.

         The table includes the Codex Classification Numbers (CCNs) of
    both the compounds and the commodities listed, to facilitate reference
    to the Guide to Codex Maximum Limits for Pesticide Residues. CCNs for
    commodities are those of the revised Classification. Commodities are
    listed in the order of the "Types" in the Classification, and within
    each Type in alphabetical order. Different Types are not differentiated
    by sub-headings, but are separated from one another by spaces. The
    Types are listed in the following order:

    Type                                               Code

    Fruits                                             01
    Vegetables                                         02
    Grasses                                            03
    Nuts and seeds                                     04
    Herbs and spices                                   05
    Mammalian products                                 06
    Poultry products                                   07
    Primary animal feed commoditiesof plant origin     11
    Secondary food commodities of plant origin         12
    Derived products of plant origin                   13

        ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs)
                                                                                                             

    Pesticide            Recommended                                                Recommended MRL
    (CCN)                maximum               Commodity                                (mg/kg)           
    Year(s) of           ADI                CCN        Name                   New                 Previous
    previous             (mg/kg bw)                                           (W=withdrawn)
    evaluation(s)
                                                                                                             

    ACEPHATE             0.03
    (095)
    1976,1979,1981,
    1982,1984,1987
                                            Residue:   acephate
          
                                            Remarks:   ADI increased
                                                                                                             

    BENOMYL              0.02
    (069)
    1973,1975,1978
    (report only),
    1983                                    Residue:   residues arising from the use of benomyl are
                                                       covered by the MRLs for carbendazim

                                            Remarks:
                                                                                                             

    ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont'd).
                                                                                                             

    Pesticide            Recommended                                                Recommended MRL
    (CCN)                maximum               Commodity                                (mg/kg)           
    Year(s) of           ADI                CCN        Name                   New                 Previous
    previous             (mg/kg bw)                                           (W=withdrawn)
    evaluation(s)
                                                                                                             

    BITERTANOL           0.01               FS 0013    Cherries               2                 1 (T) for
    (144)                                   FS 0014    Plums                                    stone fruits
    1983,1984,1986                                     (including Prunes)     2                 (1984)
    1987                                    FP 0009    Pome fruits            1                 2 (T) for
                                                                                                apple (1984)
                                            FS 0012    Stone fruits,          1                 1 (T) for
                                                       except cherries                          stone fruits
                                                       and plums                                (1984)

                                            VP 0526    Common bean            0.5               -
                                            VC 0424    Cucumber               0.5               -

                                            SO 0697    Peanut                 0.1*

                                            AL 1030    Bean forage (green)    10 dry wt         -
                                            AL 1270    Peanut forage "        20 dry wt         -

                                            Residue:   bitertanol

                                            Remarks:   ADI increased.
                                                       Temporary MRLs recommended by 1984 JMPR for
                                                       bananas and various cereal grains, forages,
                                                       straws and fodders are now converted to MRLs.
                                                                                                             

    ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont'd).
                                                                                                             

    Pesticide            Recommended                                                Recommended MRL
    (CCN)                maximum               Commodity                                (mg/kg)           
    Year(s) of           ADI                CCN        Name                   New                 Previous
    previous             (mg/kg bw)                                           (W=withdrawn)
    evaluation(s)
                                                                                                             

    BROMIDE ION          1                  ML 0812    Cattle Milk            20 (ERL)            -
    (047)
    1968,1969,1971                          Residue:   bromide ion
    1979,1981,1983
                                                                                                             

    CARBENDAZIM          0.01               FB 0018    Berries and other
    (072)                                              small fruits           5    1/             -
    1973,1976,1977,                         FP 0009    Pome fruits            5    2/             -
    1978,1983,1985
    1987                                    VD 0534    Lima bean (dry)        W    3/             2 (1973)

                                            GC 0080    Cereal grains          0.5  4/             -

                                                       Almond hulls           W
                                                       Peanut hulls           W                   0.2 (1973)
                                                                                                             

    ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont'd).
                                                                                                             

    Pesticide            Recommended                                                Recommended MRL
    (CCN)                maximum               Commodity                                (mg/kg)           
    Year(s) of           ADI                CCN        Name                   New                 Previous
    previous             (mg/kg bw)                                           (W=withdrawn)
    evaluation(s)
                                                                                                             

    CARBENDAZIM                             SO 0495    Rape seed              0.05*               -
    (cont'd)                                TN 0085    Tree nuts            0.1* 5/               -

                                            Residue:   carbendazim

                                            Remarks:   1/ Replacing separate recommendations
                                                          for grapes at 10 mg/kg and various berry fruits
                                                          at 5 mg/kg.
                                                       2/ Replacing separate recommendations for
                                                          apple and pear at the same level.
                                                       3/ Covered by MRL for beans (dry) at the same
                                                          level.
                                                       4/ Replacing separate recommendations for
                                                          barley, oats, rice, rye and wheat at the
                                                          same level.
                                                       5/ Replacing separate recommendations for
                                                          chestnuts at 0.2 mg/kg and almonds,
                                                          macadamia nuts and pecan at 0.1* mg/kg.

                                                       For a complete list of MRLs for carbendazim,
                                                       indicating the source(s) of the data on which
                                                       each limit is based, see monograph on
                                                       carbendazim in 1988 Evaluations, Part I.
                                                                                                             

    ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont'd).
                                                                                                             

    Pesticide            Recommended                                                Recommended MRL
    (CCN)                maximum               Commodity                                (mg/kg)           
    Year(s) of           ADI                CCN        Name                   New                 Previous
    previous             (mg/kg bw)                                           (W=withdrawn)
    evaluation(s)
                                                                                                             

    DELTAMETHRIN         0.01               ML 0106    Milks                  0.01*               -
    (135)
    1980,1981,1982,                         CM 0654    Wheat bran,
    1984,1985,1986,                                    unprocessed            5 1/                2 (1987)
    1987
                                            CF 1212    Wheat wholemeal        1 1/                0.5 (1987)

                                            Residue:   deltamethrin

                                            Remarks:   1/ MRL accommodates post-harvest uses on
                                                          wheat.
                                                                                                             

    DIMETHIPIN           0.02               OC 0691    Cotton seed oil,
    (151)                                                crude                0.1                 -
    1985,1987                               OR 0691    Cotton seed oil,
                                                         edible               0.02*               -
                                            OR 0702    Sunflower seed oil,
                                                         edible               0.02*               -

                                            Residue:   dimethipin

                                            Remarks:   TADI replaced by ADI at higher level.
                                                       TMRLs replaced by MRLs
                                                                                                             

    ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont'd).
                                                                                                             

    Pesticide            Recommended                                                Recommended MRL
    (CCN)                maximum               Commodity                                (mg/kg)           
    Year(s) of           ADI                CCN        Name                   New                 Previous
    previous             (mg/kg bw)                                           (W=withdrawn)
    evaluation(s)
                                                                                                             

    DIMETHOATE           0.01               FT 0305    Olives                 1                   2 (1967)
    (027)
    1965,1966,1967,                         GC 0654    Wheat                  0.2                 -
    1970, 1973 (see
    formothion),1977,                       OR 0305    Olive oil, refined     0.05                -
    1978,1983,1984,                         DM 0305    Olives, processed      0.05                -
    1986,1987
                                            Residue:   dimethoate
                                                                                                             

    ETHYLENETHIOUREA     0.002              VO 0447    Sweet corn             W                   0.01* (1974)
    (108)                (1993)                        (corn-on-the-cob)
    1974,1977,1986
    1987                                    GC 0645    Maize                  W                   0.01* (1974)

                                            Residue:   ethylenethiourea

                                            Remarks:   TADI extended at same level
                                                                                                             

    ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont'd).
                                                                                                             

    Pesticide            Recommended                                                Recommended MRL
    (CCN)                maximum               Commodity                                (mg/kg)           
    Year(s) of           ADI                CCN        Name                   New                 Previous
    previous             (mg/kg bw)                                           (W=withdrawn)
    evaluation(s)
                                                                                                             

    ETRIMFOS             0.003              FP 0226    Apple                  1                   0.5 (1982)
    (123)                                   FS 0240    Apricot                0.05                0.2 (1982)
    1980,1982,1986,                         FS 0247    Peach                  0.05                0.1 (1982)
    1987
                                            VS 0620    Artichoke, Globe       0.2                 0.5 (1982)
                                            VB 0402    Brussels sprouts       0.05                0.5 (1982)
                                            VB 0404    Cauliflower            0.05                0.2 (1982)
                                            VL 0480    Kale                   0.5                 0.1 (1982)
                                            VL 0482    Lettuce, Head          2 (T)               0.5 (1982)
                                            VO 0448    Tomato                 0.5                 0.2 (1982)

                                            GC 0640    Barley                 5 Po                10 (1980)
                                            GC 0645    Maize                  5 Po                10 (1980)
                                            GC 0654    Wheat                  5 Po                10 (1980)

                                            CM 0654    Wheat bran,
                                                       unprocessed            10 PoG              20 (1980)
                                                                                                             

    ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont'd).
                                                                                                             

    Pesticide            Recommended                                                Recommended MRL
    (CCN)                maximum               Commodity                                (mg/kg)           
    Year(s) of           ADI                CCN        Name                   New                 Previous
    previous             (mg/kg bw)                                           (W=withdrawn)
    evaluation(s)
                                                                                                             

    ETRIMFOS                                CF 1211    Wheat flour            1 PoG               2 (1980)
    (cont'd)                                CF 1212    Wheat wholemeal        5 PoG               10 (1980)

                                            Residue:   sum of etrimfos and its oxygen analogue

                                            Remarks:   Note changed definition of residue. All
                                                       decreases in limits are to accommodate the
                                                       change.
                                                       Po: MRL covers post-harvest uses.
                                                       PoG: MRL covers post-harvest uses on the
                                                            cereal grain.
                                                                                                             

    FENITROTHION         0.005
    (037)
    1969,1974,1976,                         Residue:   fenitrothion
    1977,1979,1982,
    1983,1984,1986                          Remarks:   ADI slightly increased.
    1987
                                                                                                             

    ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont'd).
                                                                                                             

    Pesticide            Recommended                                                Recommended MRL
    (CCN)                maximum               Commodity                                (mg/kg)           
    Year(s) of           ADI                CCN        Name                   New                 Previous
    previous             (mg/kg bw)                                           (W=withdrawn)
    evaluation(s)
                                                                                                             

    FENVALERATE          0.02               VB 0402    Brussels sprouts       5                   2 (1986)
    (119)
    1979,1981,1982,
    1984,1985,1986,
    1987                                    Residue:   fenvalerate
                                                                                                             

    GLYPHOSATE           0.3                GC 0654    Wheat                  5                   10 (1987)
    (158)
    1986,1987                               CM 0654    Wheat bran,
                                                       unprocessed            40                  50 (1987)

                                            CF 1211    Wheat flour            0.5                 -
                                            CF 1212    Wheat wholemeal        5                   -

                                            Residue:   glyphosate
                                                                                                             

    ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont'd).
                                                                                                             

    Pesticide            Recommended                                                Recommended MRL
    (CCN)                maximum               Commodity                                (mg/kg)           
    Year(s) of           ADI                CCN        Name                   New                 Previous
    previous             (mg/kg bw)                                           (W=withdrawn)
    evaluation(s)
                                                                                                             

    IMAZALIL             0.01               VR 0589    Potato                 5 (T) 1/            5 (1984) 2/
    (110)
    1977,1980,1984,                         Residue imazalil
    1985,1986
                                            Remarks:   1/ MRL refers to post-harvest use, and applies
                                                          to seed potatoes washed before analysis.
                                                       2/ The limit proposed in 1984 was temporary only
                                                          because the ADI was temporary at that time.
                                                                                                             

    ISOFENFOS           0.001               VA 0385    Onion, Bulb            0.1                 -
    (131)                                   VR 0589    Potato                 0.1                 -
    1981,1982,1984,
    1985,1986                               Residue:   sum of isofenphos and its oxygen analogue

                                            Remarks:
                                                                                                             

    METHACRIFOS          0.003
    (125)                (1990)
    1980,1982,1986                              Residue:   methacrifos

                                            Remarks:   TADI extended at higher level.
                                                                                                             

    ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont'd).
                                                                                                             

    Pesticide            Recommended                                                Recommended MRL
    (CCN)                maximum               Commodity                                (mg/kg)           
    Year(s) of           ADI                CCN        Name                   New                 Previous
    previous             (mg/kg bw)                                           (W=withdrawn)
    evaluation(s)
                                                                                                             

    METHICARB            0.001              VS 0620    Artichoke, Globe       0.05*               -
    (132)                                   TN 0666    Hazelnuts              0.05*               -
    1981,1983,1984,
    1985,1986,1987                          Residue:   sum of methiocarb, its sulphoxide and its
                                                       sulphone, expressed as methiocarb

                                            Remarks:   note changed definition of residue, previously
                                                       "sum of methiocarb, its sulphoxide and its
                                                       sulphone."
                                                                                                             

    METHOMYL             0.01               PC 0001    Citrus fruits          1                   2 (1975)
    (094)                (1989)             FP 0009    Pome fruits            2 1/                -
    1975,1976,1977
    1978,1986,1987                          VS 0624    Celery                 0.2                 3 (1975)
                                            VO 0448    Tomato                 0.2                 1 (1975)

                                            AS 0640    Barley straw
                                                       and fodder, dry        5                   10 (1975)
                                                                                                             

    ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont'd).
                                                                                                             

    Pesticide            Recommended                                                Recommended MRL
    (CCN)                maximum               Commodity                                (mg/kg)           
    Year(s) of           ADI                CCN        Name                   New                 Previous
    previous             (mg/kg bw)                                           (W=withdrawn)
    evaluation(s)
                                                                                                             

    METHOMYL                                AS 0647    Oat straw
    (cont'd)                                           and fodder, dry        5                   10 (1975)
                                            AS 0654    Wheat straw
                                                       and fodder, dry        5                   10 (1975)

                                            Residue:   sum of methomyl and methyl hydroxythioacetimidate
                                                       ("methomyl oxime"), expressed as methomyl

                                            Remarks:   1/ Replacing TMRL for apple at same level
                                                                                                             

    METHOPRENE           0.1                GC 0080    Cereal grains          5 Po                10 (1984)
    (147)
    1984,1986,1987                          CM 0654    Wheat bran,
                                                       unprocessed            10 PoG              20 for bran
                                                                                                  (1984)
                                            OR 0645    Maize oil, edible      0.2*                -
                                            CF 1211    Wheat flour            2 PoG               5 (1984)
                                            CF 1212    Wheat wholemeal        5 PoG               10 (1984)

                                            Residue:   methoprene

                                            Remarks:   Po: MRL covers post-harvest uses.
                                                       PoG: MRL covers post-harvest use on the
                                                            cereal grain.
                                                                                                             

    ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont'd).
                                                                                                             

    Pesticide            Recommended                                                Recommended MRL
    (CCN)                maximum               Commodity                                (mg/kg)           
    Year(s) of           ADI                CCN        Name                   New                 Previous
    previous             (mg/kg bw)                                           (W=withdrawn)
    evaluation(s)
                                                                                                             

    OMETHOATE            0.0003             FT 0305    Olives                 W                   2 (1978)
    (055)
    1971,1975,1978,                         Residue:   omethoate
    1979,1981,1984,
    1985,1986,1987                          Remarks:
                                                                                                             

    PACLOBUTRAZOL        0.1                FP 0226    Apple                  0.2                 -
    (161)                                   FS 0012    Stone fruits           0.05                -

                                            Residue:   paclobutrazol

                                            Remarks:
                                                                                                             

    PERMETHRIN           0.05*              VA 0389    Spring onion           0.5                 5 (1979)
    (120)
    1979,1980,1981,      * Applies to the nominal 40% cis-,
    1982,1983,1984,      50% trans- and 25% cis-, 75% trans-
    1985,1986,1987       materials only

                                            Residue:   permethrin (sum of isomers)
                                                                                                             

    ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont'd).
                                                                                                             

    Pesticide            Recommended                                                Recommended MRL
    (CCN)                maximum               Commodity                                (mg/kg)           
    Year(s) of           ADI                CCN        Name                   New                 Previous
    previous             (mg/kg bw)                                           (W=withdrawn)
    evaluation(s)
                                                                                                             

    PHENOTHRIN           0.07               GC 0080    Cereal grains          W                   5 (1979)
    (127)                for                GC 0640    Barley                 2 Po                5 for cereal
    1979,1980,           "d-phenothrin"     GC 0651    Sorghum                2 Po                grains
    1982,1984,                              GC 0654    Wheat                  2 Po                (1979)
    1987
                                            CM 0649    Rice, husked           0.1                 -
                                            CM 0654    Wheat bran,
                                                         unprocessed          5 PoG               15 (1979)

                                            CF 1211    Wheat flour            1 PoG               -
                                            CF 1210    Wheat germ             5 PoG               -
                                            CF 1212    Wheat wholemeal        2 PoG               -

                                            Residue:   phenothrin (sum of (+)-trans- and (+)-cis-isomers)

                                            Remarks:   TADI replaced by ADI at higher level. TMRLs
                                                       replaced by MRLs.
                                                       Po: MRL covers post-harvest uses.
                                                       PoG: MRL covers post-harvest use on the cereal grain.
                                                                                                             

    ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont'd).
                                                                                                             

    Pesticide            Recommended                                                Recommended MRL
    (CCN)                maximum               Commodity                                (mg/kg)           
    Year(s) of           ADI                CCN        Name                   New                 Previous
    previous             (mg/kg bw)                                           (W=withdrawn)
    evaluation(s)
                                                                                                             

    PHOSMET              0.02               VO 0447    Sweet corn
    (103)                                                (corn-on-the-cob)    0.05                0.5 (1986)
    1976, 1977 (corr,
    to 1976), 1978,                         GC 0645    Maize                  0.05                0.5 (1986)
    1979,1981,1984,
    1985,1986,1987,                         Residue:   sum of phosmet and its oxygen analogue
                                                                                                             

    PHOXIM               0.001              VB 0403    Cabbage, Savoy         0.05 *              -
    (141)                                   VA 0385    Onion, Bulb            0.05 *              -
    1982,1983,1984,
    1986,1987                               MM 0822    Sheep meat             0.5 (fat)           1 (fat) (1983)

                                            Residue:   phoxim

                                            Remarks:   limit for sheep meat covers veterinary uses.
                                                                                                             

    THIOMETON            0.003              VL 0469    Chicory leaves 1/      0.5                 0.5 for
    (076)                                                                                         chicory
    1969,1973,1976,                                                                               (1976)
    1979                                    Residue:   sum of thiometon, its sulphoxide and sulphone,
                                                       expressed as thiometon

                                            Remarks:   1/ note changed commodity description
                                                                                                             

    ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont'd).
                                                                                                             

    Pesticide            Recommended                                                Recommended MRL
    (CCN)                maximum               Commodity                                (mg/kg)           
    Year(s) of           ADI                CCN        Name                   New                 Previous
    previous             (mg/kg bw)                                           (W=withdrawn)
    evaluation(s)
                                                                                                             

    THIOPHANATEMETHYL    0.08                          All commodities        W
    (077)
    1973,1975,1977                          Residue:   residues arising from the use of thiophanatemethyl
    1978                                               are covered by the MRLs for carbendazim

                                            Remarks:
                                                                                                             

    TOLYLFLUANID         0.1                FB 0021    Currants, Black,
    (162)                                                Red, White           5                   -
                                            FP 0009    Pome fruits            5                   -
                                            FB 0275    Strawberry             3                   -

                                            VC 0425    Gherkin                2                   -
                                            VL 0482    Lettuce, Head          1                   -
                                            VO 0448    Tomato                 2                   -

                                            Residue:   tolylfluanid

                                            Remarks:
                                                                                                             

    ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont'd).
                                                                                                             

    Pesticide            Recommended                                                Recommended MRL
    (CCN)                maximum               Commodity                                (mg/kg)           
    Year(s) of           ADI                CCN        Name                   New                 Previous
    previous             (mg/kg bw)                                           (W=withdrawn)
    evaluation(s)
                                                                                                             

    TRIADIMEFON          0.03               FI 0345    Mango                  0.1*                -
    (133)
    1979,1981,1983,                         Residue:   sum of triadimefon and triadimenol
    1984,1985,1986,
    1987                                    Remarks:   the PHIs to which existing MRLs for certain cereal
                                                       grains and straws are related are decreased.
                                                       Numerical values of MRLs are unchanged.
                                                                                                             

    VAMIDOTHION          0.008
    (078)                                   Residue:   sum of vamidothion, its sulphoxide and sulphone,
    1973,1982,1985,                                    expressed as vamidothion
    1987
                                            Remarks:   TADI replaced by ADI at higher level.
                                                       THRLs replaced by MRLs
                                                                                                             

    VINCLOZOLIN          0.07
    (159)
    1986,1987                               Residue:   sum of vinclozolin and all metabolites containing 
                                                       the 3,5-dichloroantline moiety, expressed as
                                                       vinclozolin.

                                            Remarks:   TADI replaced by ADI at higher level.
                                                       TMRLs replaced by MRLs
                                                                                                             
        





















    See Also:
       Toxicological Abbreviations