1976 EVALUATIONS OF SOME PESTICIDE RESIDUES IN FOOD
THE MONOGRAPHS
The content of this document is the result of the deliberations of the
Joint Meeting of the FAO Panel of Experts on Pesticide Residues and
the Environment and the WHO Expert Group on Pesticide Residues, which
met in Rome, 22 - 30 November 1976.*
FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS
Rome, 1977
* Pesticide Residues in Food: Report of the 1976 Joint Meeting of the
FAO Panel of Experts on Pesticide Residues and the Environment and the
WHO Expert Group on Pesticide Residues, WHO Technical Report, Series
No. 612, 1977; Plant Production and Protection Series No. 8, 1977.
This document contains summaries of data considered by the Joint
Meeting of the FAO Panel of Experts on Pesticide Residues and the
Environment and the WHO Expert Group on Pesticide Residues in arriving
at recommendations for acceptable daily intakes, tolerances and
methods of analysis.
A summary report of the 1976 Joint Meeting* has also been
published which contains general considerations, including the
principles adopted for the evaluation and a summary of the results of
evaluation of a number of pesticide residues.
* Pesticide Residues in Food. Report of the 1976 Joint Meeting of the
FAO Panel of Experts on Pesticide Residues and the Environment and the
WHO Expert Group on Pesticide Residues, WHO Technical Report Series
No. 612, 1977; Plant Production and Protection Series No. 8, 1977.
M-84
ISBN 92-5-100442-0
(C) FAO and WHO 1977
CONTENTS
List of attendees
Introduction
The Monographs
Acephate
Bioresmethrin*
Captafol*
Carbaryl*
Carbendazim*
Carbofuran (text is not available)
Carbophenothion*
Cartap
Chlormequat*
Dialifos
Diphenylamine*
Diquat*
Dodine*
Edifenphos
Fenitrothion*
Maleic hydrazide
Methamidophos
Methomyl*
Paraquat*
Phosalone*
Phosmet
Pirimicarb
Pirimiphos-methyl*
Thiometon*
ANNEX 1 - Acceptable daily intakes, residue limits and guideline
levels recommended at the 1976 Meeting
* Addendum
LIST OF ATTENDEES
Members of the FAO Panel of Experts on Pesticide Residues and the
Environment:
Dr A.F.H. Besemer, Head, Pesticides Division, Plant Protection
Service, Ministry of Agriculture, Wageningen, Netherlands
Professor G. Bressau, Head, Pesticides Unit, Division of Food
Chemistry, Federal Health Office, Berlin (West)
Mr F. Bro-Rasmusen, National Food Institute, Division of
Pesticides and Contaminants, Soborg, Copenhagen, Denmark
(Rapporteur)
Mr J.G. Cummings, Chief, Chemistry Branch, Registration Division,
Office of Pesticide Programs, Environmental Protection Agency,
Washington, DC, USA
Mr J.T. Snelson, Pesticides Coordinator, Department of Primary
Industry, Canberra, Australia (Chairman)
Dr E.M. Thain, Deputy Directory Tropical Products Institute,
London, England
Members of the WHO Expert Group on Pesticide Residues:
Dr V. Benes, Chief, Toxicology Department, Institute of Hygiene
and Epidemiology, Prague, Czechoslovakia (Rapporteur)
Mr D.J. Clegg, Pesticide Section, Toxicological Evaluation
Division, Health Protection Branch, Department of National Health
and Welfare, Ottawa, Canada (Vice-Chairman)
Professor I. Nir, Department of Clinical Pharmacology, Ministry
of Health, Jerusalem, Israel
Professor F.K. Ohnesorge, Pharmacological and Technological
Institute, Düsseldorf, Federal Republic of Germany
Professor C. Schlatter, Institute of Toxicology, Federal
Polytechnic, and University of Zürich, Schwerzenbach, Zürich,
Switzerland
Dr M. van Logten, Laboratory for General Toxicology, National
Institute of Public Health, Bilthoven, Netherlands
Observer invited by FAO:
Dr A.J. Pieters, Chairman, Codex Committee on Pesticide Residues,
Directorate of Public Health, Foodstuffs Division, Leidschendam,
Netherlands
Secretariat:
Dr C. Agthe, Chief, Food Additives, WHO, Geneva, Switzerland
Dr R. Baron, Health Effects Research Laboratory, Environmental
Research Center, United States Environmental Protection Agency,
Research Triangle Park, USA (Temporary Adviser)
Dr L.G. Ladomery, Joint FAO/WHO Food Standards Programme, Rome,
Italy
Dr R. Leski, Chemical Residue and Pollution Section, Joint
FAO/IAEA Division of Atomic Energy in Agriculture, International
Atomic Energy Agency, Vienna, Austria
Mr A.F. Machin, Senior Research Officer, Central Veterinary
Laboratory, Ministry of Agriculture, Weybridge, England
(Consultant)
Dr E. Middleton, Food Directorate, Health Protection Branch,
Department of National Health and Welfare, Ottawa (Temporary
Adviser)
Dr Orville E. Paynter, Chief, Toxicology Branch, Registration
Division, Office of Pesticide Programs, US Environmental
Protection Agency, Washington, DC, USA (Temporary Adviser)
Dr E.E. Turtle, Pesticides Specialist, Plant Protection Service,
FAO, Rome, Italy (Joint Secretary)
Dr G. Vettorazzi, Scientist, Food Additives, WHO, Geneva,
Switzerland (Joint Secretary)
INTRODUCTION
A Joint Meeting of the FAO Panel of Experts on Pesticide Residues
and the Environment and the WHO Expert Group on Pesticide Residues was
held in Rome from 22 to 30 November 1976. The report on the session
which is entitled "Report of the 1976 Joint Meeting of the FAO Panel
of Experts on Pesticide Residues and the Environment and the WHO
Expert Group on Pesticide Residues" provides information on the
general principles followed and considerations of the meeting. It also
contains a summary of the evaluations made on residues in foods of the
various pesticides considered at the session. The present document
contains recommendations for acceptable daily intakes, for maximum
acceptable residue levels and for methods of analysis together with
summaries of the data considered by the Meeting in making these
recommendations.
As much relevant information as possible has been included in the
monographs. This has been obtained from the published literature
wherever possible, but other sources of information have also been
used. Early and complete publications of the results of research in
this field are very important, particularly of that part which could
form the basis for estimation of acceptable daily intakes and
appropriate residue levels. Publication allows the research to be
scrutinized and criticized by scientists from disciplines not
necessarily represented at the meeting. Data contained in unpublished
reports is less satisfactory and, when considered, must be complete
and nonconfidential and indicate authorship.
Some of the compounds considered at this meeting have been
previously evaluated and reported on in earlier publications. If only
a limited amount of additional information of these compounds has
become available at this meeting, only this latter information is
summarized in the pertinent monograph, and reference is made to the
previously published evaluation, which should also be consulted by the
reader who wishes to obtain a complete evaluation of the compound.
Such monograph addenda are indicated by an asterisk in the "Contents",
p. iii.
The Annex at the end of this volume of monographs is a
reproduction of Annex I of the Report of the 1976 Joint Meeting and
gives a summary of the recommendations concerning acceptable daily
intakes, residue limits and guideline levels recommended at the 1976
Meeting.
NOTE TO THE READER
Any comments on evaluation for acceptable daily intake should be
addressed to:
Food Additives Unit
World Health Organization
Geneva, Switzerland
Any comments on residues in food and their evaluation should be
addressed to:
Plant Protection Service
Plant Production and Protection Division
Food and Agriculture Organization
Rome, Italy