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NICOTINIC ACID
ICSC: 1702
Peer-Review Status: 08.04.2008 Validated
3-Pyridinecarboxylic acid
3-Carboxypyridine
Pyridine-beta-carboxylic acid
Niacin
CAS #: 59-67-6 RTECS #: QT0525000
EINECS #: 200-441-0
    Formula: C6H5NO2/HOOC5H4N
Molecular mass: 123.1

TYPES OF HAZARD
/ EXPOSURE
ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE-FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, foam, powder, carbon dioxide. 
EXPLOSION Finely dispersed particles form explosive mixtures in air.  Prevent deposition of dust. Closed system, dust explosion-proof electrical equipment and lighting.   
 
EXPOSURE   PREVENT DISPERSION OF DUST!   
Inhalation Cough.  Avoid inhalation of dust.  Fresh air, rest. 
Skin   Protective gloves.  Rinse skin with plenty of water or shower. 
Eyes Redness.  Wear safety goggles.  Rinse with plenty of water (remove contact lenses if easily possible). 
Ingestion Flushing of the face.  Do not eat, drink, or smoke during work.  Rinse mouth. Give one or two glasses of water to drink. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.   
EC Classification
 
UN Classification
 
GHS Classification
Signal: Warning
Causes eye irritation
Harmful to aquatic life 

EMERGENCY RESPONSE SAFE STORAGE
  Store in an area without drain or sewer access. Separated from strong acids, bases and oxidants. 

IMPORTANT DATA
Physical State; Appearance
WHITE CRYSTALS OR CRYSTALLINE POWDER. 

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air. 

Chemical dangers
On combustion, forms toxic gases including nitrogen oxides. Reacts with oxidants, strong acids and bases. 

Occupational exposure limits
TLV not established.
MAK (not established):. 

Routes of exposure
 

Inhalation risk
A nuisance-causing concentration of airborne particles can be reached quickly when dispersed, especially if powdered. 

Effects of short-term exposure
The substance is mildly irritating to the eyes. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Melting point: 236.6°C
Density: 1.5 g/cm³
Solubility in water, g/100ml at 20°C: 1.8 (moderate)
Flash point: 193°C c.c.
Auto-ignition temperature: 580°C
Explosive limits, vol% in air: 25 - ?
Octanol/water partition coefficient as log Pow: -2.43  
The substance is harmful to aquatic organisms. 

NOTES
 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.
    See Also:
       Toxicological Abbreviations
       Nicotinic acid (SIDS)