2-NITROANISOLE (ICSC)

2-NITROANISOLE	ICSC: 1520

Date of Peer Review: April 2004

Benzene, 1-methoxy-2-nitro-
1-Methoxy-2-nitrobenzene
o-Nitrophenyl methyl ether
o-Nitroanisole

CAS #

91-23-6

NO₂C₆H₄OCH₃ / C₇H₇NO₃

RTECS #

BZ8790000

Molecular mass: 153.1

UN #

2730

EC #

609-047-00-7

TYPES OF HAZARD / EXPOSURE	ACUTE HAZARDS / SYMPTOMS	PREVENTION	FIRST AID / FIRE FIGHTING
FIRE	Combustible.	NO open flames.	Carbon dioxide, foam, powder.
EXPLOSION

EXPOSURE		AVOID ALL CONTACT!
Inhalation	Blue lips or finger nails. Dizziness. Headache. Nausea. Confusion.	Ventilation, local exhaust, or breathing protection.	Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Skin	Dry skin.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes		Safety goggles, or eye protection in combination with breathing protection.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion	(See Inhalation).	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Give a slurry of activated charcoal in water to drink. Rest. Refer for medical attention.

SPILLAGE DISPOSAL

PACKAGING & LABELLING

Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT let this chemical enter the environment. Personal protection: filter respirator for organic gases and vapours. Chemical protection suit.

EU Classification
Symbol: T
R: 45-22
S: 53-45
Note: [E]
UN Classification
UN Hazard Class: 6.1
UN Pack Group: III

EMERGENCY RESPONSE

STORAGE

Transport Emergency Card: TEC (R)-61GT1-III.

Well closed.

IPCS
International
Programme on
Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities © IPCS, CEC 1999

SEE IMPORTANT INFORMATION ON BACK

2-NITROANISOLE

ICSC: 1520

IMPORTANT DATA

PHYSICAL STATE; APPEARANCE:
COLOURLESS TO YELLOW-RED LIQUID

PHYSICAL DANGERS:
The vapour is heavier than air.

CHEMICAL DANGERS:
On combustion, forms toxic and corrosive fumes.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
MAK: Carcinogen category: 2; (DFG 2003).

ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation and by ingestion.

INHALATION RISK:
A harmful concentration of airborne particles can be reached quickly on spraying.

EFFECTS OF SHORT-TERM EXPOSURE:
Exposure at high levels may result in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The liquid defats the skin. This substance is possibly carcinogenic to humans. The substance may have effects on the blood, resulting in anaemia.

PHYSICAL PROPERTIES

Boiling point: 277°C
Melting point: 10°C
Relative density (water = 1): 1.25
Solubility in water: at 20 °C none
Vapour pressure, kPa at 30°C: 0.004
Relative vapour density (air = 1): 5.29

Flash point: 124°C
Auto-ignition temperature: 464°C
Explosive limits, vol% in air: 1.04-66
Octanol/water partition coefficient as log Pow: 1.73

ENVIRONMENTAL DATA

The substance is harmful to aquatic organisms.

NOTES

Do NOT take working clothes home. Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.

ADDITIONAL INFORMATION

LEGAL NOTICE

Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information

    See Also:
       Toxicological Abbreviations
       Nitroanisole, 2- (IARC Summary & Evaluation, Volume 65, 1996)