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2,3,7,8-TETRACHLORODIBENZO-p-DIOXIN
ICSC: 1467
Peer-Review Status: 26.11.2003 Validated
Dibenzo [b,e] [1,4]dioxin, 2,3,7,8-tetrachloro-
2,3,7,8-TCDD
2,3,7,8-Tetrachloro-1,4-dioxin 
CAS #: 1746-01-6 RTECS #: HP3500000
UN #: 2811
EINECS #: 217-122-7
    Formula: C12H4Cl4O2
Molecular mass: 322

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Gives off irritating or toxic fumes (or gases) in a fire.    In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION      
 
EXPOSURE   AVOID ALL CONTACT!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Symptoms may be delayed.  Use appropriate engineering controls.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! See Inhalation. Redness. Pain.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Give a slurry of activated charcoal in water to drink. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Personal protection: chemical protection suit including self-contained breathing apparatus.   
EC Classification
 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: I 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT2-I.  Separated from food and feedstuffs. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS-TO-WHITE NEEDLE-LIKE CRYSTALS. 

Physical dangers
 

Chemical dangers
Decomposes at 750-800°C. Decomposes under the influence of UV light. This produces chlorine. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):.
MAK (inhalable fraction): 10^-^8 mg/m³; Carcinogen category: 4; Peak limitation category: II(8); Pregnancy risk group: C; Skin absorption (H); (DFG 2003). 

Routes of exposure
The substance can be absorbed into the body by inhalation of dust, through the skin and by ingestion. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the cardiovascular system, gastrointestinal tract, liver, nervous system and endocrine system. The effects may be delayed. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. May cause chloracne. The substance may have effects on the bone marrow, endocrine system, immune system, liver and nervous system. This substance is carcinogenic to humans. Animal tests show that this substance possibly causes toxicity to human reproduction or development. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Melting point: 305-306°C
Density: 1.8 g/cm³
Solubility in water: none
Vapour pressure at 25°C: negligible
Octanol/water partition coefficient as log Pow: 6.8/7.02  
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to soil contamination. Bioaccumulation of this chemical may occur in fish, plants, mammals and milk. It is strongly advised not to let the chemical enter into the environment. 

NOTES
This chemical is only produced for research purposes, but could be generated as a by-product from chemical processes or fires.
Card has been partly updated in April 2005.
See section Occupational Exposure Limits. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.
    See Also:
       Toxicological Abbreviations