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METHYL 2-CYANOACRYLATE
ICSC: 1272
Peer-Review Status: 10.04.2000 Validated
2-Propenoic acid, 2-cyano-, methyl ester
2-Cyanoacrylic acid methyl ester
Mecrylate 
CAS #: 137-05-3 RTECS #: AS7000000
EC #: 607-235-00-3
EINECS #: 205-275-2
    Formula: C5H5NO2 / CH2=C(CN)COOCH3
Molecular mass: 111.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use foam, powder, carbon dioxide. NO water. 
EXPLOSION Above 79°C explosive vapour/air mixtures may be formed.  Above 79°C use a closed system and ventilation.  In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water. 
 
EXPOSURE   AVOID ALL CONTACT!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Cough. Headache. Sore throat.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Dry skin. Redness. Pain.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion   Do not eat, drink, or smoke during work.   

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: face shield and filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Remove all ignition sources. Do NOT wash away into sewer. Absorb liquid in sand or inert absorbent. Let solidify.   
EC Classification
Symbol: Xi; R: 36/37/38; S: (2)-23-24/25-26 
UN Classification
 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
  Separated from incompatible materials. See Chemical Dangers. Well closed. Store only if stabilized. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID. 

Physical dangers
 

Chemical dangers
The substance rapidly polymerizes , especially under the influence of moisture. Decomposes on heating and on burning. This produces toxic and irritating fumes and gases including nitrogen oxides. 

Occupational exposure limits
TLV: 0.2ppm as TWA; (ACGIH 2008).
MAK: 2 ppm, 9.2 mg/m³; Peak limitation category: I(1); Pregnancy risk group: D; (DFG 2008). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour. 

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The vapour is irritating to the eyes and respiratory tract. Inhalation of the vapour may cause asthmatic reactions. See Notes. Immediately glues (sticks to) biological tissues. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 66°C
Melting point: -40°C
Relative density (water = 1): 1.1
Vapour pressure, Pa at 25°C: 24
Relative vapour density (air = 1): 3.8
Relative density of the vapour/air-mixture at 20°C (air = 1): 1
Flash point: 79°C
Octanol/water partition coefficient as log Pow: 0.03 (estimated) 
 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation are therefore essential.
Anyone who has shown symptoms of asthma due to this substance should avoid all further contact with this substance.
An added stabilizer or inhibitor can influence the toxicological properties of this substance, consult an expert.
Card has been partly updated in April 2005. See section Occupational Exposure Limits.
Card has been partially updated in February 2009: see Occupational Exposure Limits. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations