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TYPES OF HAZARD / EXPOSURE |
ACUTE HAZARDS / SYMPTOMS | PREVENTION | FIRST AID / FIRE FIGHTING |
| FIRE | Extremely flammable. Many reactions may cause fire or explosion. Gives off irritating or toxic fumes (or gases) in a fire. | NO open flames, NO sparks and NO smoking. | Shut off supply; if not possible and no risk to surroundings, let the fire burn itself out. In other cases extinguish with powder, carbon dioxide. |
| EXPLOSION | Gas/air mixtures are explosive. | Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT expose to friction or shock. Prevent build-up of electrostatic charges (e.g., by grounding). | Combat fire from a sheltered position. |
| EXPOSURE | AVOID ALL CONTACT! | IN ALL CASES CONSULT A DOCTOR! | |
| Inhalation | Headache. Laboured breathing. Shortness of breath. Sore throat. Vomiting. Malaise. Symptoms may be delayed. See Notes. | Use ventilation, local exhaust or breathing protection. | Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. |
| Skin | Redness. Burning sensation. Pain. Frostbite. | Cold-insulating gloves. | ON FROSTBITE: rinse with plenty of water, do NOT remove clothes. Refer for medical attention . Wear protective gloves when administering first aid. |
| Eyes | Redness. Pain. | Wear face shield or eye protection in combination with breathing protection. | First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. |
| Ingestion | Do not eat, drink, or smoke during work. | ||
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SPILLAGE DISPOSAL
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PACKAGING & LABELLING |
| Evacuate danger area! Consult an expert! Ventilation. Personal protection: complete protective clothing including self-contained breathing apparatus. |
EC Classification Symbol: T; R: 45; S: 53-45 UN Classification GHS Classification |
| EMERGENCY RESPONSE | SAFE STORAGE |
| Solutions of diazomethane should not be stored. See Notes. |
| IMPORTANT DATA | |
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Physical State; Appearance YELLOW GAS.
Physical dangers
Chemical dangers
Occupational exposure limits |
Routes of exposure The substance can be absorbed into the body by inhalation.
Inhalation risk
Effects of short-term exposure
Effects of long-term or repeated exposure |
| PHYSICAL PROPERTIES | ENVIRONMENTAL DATA |
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Boiling point: -23°C Melting point: -145°C Relative density (water = 1): 1.45 Solubility in water: reaction Relative vapour density (air = 1): 1.4 Flash point: Flammable gas Auto-ignition temperature: 100°C (explosion) |
| NOTES |
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Because of its toxicity and its explosive nature, diazomethane is freshly prepared in situ and used in solution of ether or dioxane. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Immediate administration of an appropriate spray, by a doctor or a person authorized by him/her, should be considered. The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. The relation between odour and the occupational exposure limit cannot be indicated. The recommendations on this Card also apply to concentrated solutions of diazomethane. Card has been partly updated in April 2005. See section Occupational Exposure Limits. |
| ADDITIONAL INFORMATION |
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See Also:
Toxicological Abbreviations
Diazomethane (IARC Summary & Evaluation, Volume 7, 1974)