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PICLORAMICSC: 1246
4-Amino-3,5,6-trichloro-2-pyridinecarboxylic acid
4-Amino-3,5,6-trichloropicolinic acid
June 2012
CAS #: 1918-02-1
EC Number: 217-636-1

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Gives off irritating or toxic fumes (or gases) in a fire.    NO open flames.    Use water spray, foam, powder, carbon dioxide.   

   
  SYMPTOMS PREVENTION FIRST AID
Inhalation No acute symptoms expected.  Avoid inhalation of dust.  Fresh air, rest. 
Skin No acute symptoms expected.  Protective gloves.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes No acute symptoms expected.  Wear safety goggles.  Rinse with plenty of water (remove contact lenses if easily possible). 
Ingestion No acute symptoms expected.  Do not eat, drink, or smoke during work.  Rinse mouth. 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

excl mark;warncancer;health haz
WARNING
Harmful if swallowed
May cause damage to liver through prolonged or repeated exposure
Harmful to aquatic life 

Transportation
UN Classification
 

STORAGE
Dry. Keep in a well-ventilated room. Separated from : see Chemical Dangers. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access. 
PACKAGING
 
PICLORAM ICSC: 1246
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS CRYSTALS OR WHITE POWDER WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
Decomposes on heating. This produces nitrogen oxides (see ICSC 0067, ICSC 0930) and hydrogen chloride (see ICSC 0163). Reacts with strong acids, strong bases and strong oxidants. This generates fire and explosion hazard. 

Formula: C6H3Cl3N2O2
Molecular mass: 241.5
Melting point: No melting point; decomposes at 190°C
Solubility in water, mg/l at 25°C: 430 (very poor)
Octanol/water partition coefficient as log Pow: 1.9
Vapour pressure: negligible 


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by ingestion. 

Effects of short-term exposure
 

Inhalation risk
Evaporation at 20°C is negligible; a nuisance-causing concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered. 

Effects of long-term or repeated exposure
The substance may have effects on the liver. 


OCCUPATIONAL EXPOSURE LIMITS
TLV: 10 mg/m3, as TWA; A4 (not classifiable as a human carcinogen) 

ENVIRONMENT
The substance is harmful to aquatic organisms. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
Carrier solvents used in commercial formulations may change physical and toxicological properties.
Do NOT take working clothes home. 

ADDITIONAL INFORMATION
  EC Classification
 

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    See Also:
       Toxicological Abbreviations
       Picloram (IARC Summary & Evaluation, Volume 53, 1991)