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CRUFOMATE
ICSC: 1143
Peer-Review Status: 25.10.1995 Validated
4-tert-Butyl-2-chlorophenyl methyl methylphosphoramidate
Amidophos 
CAS #: 299-86-5 RTECS #: TB3850000
UN #: 2783
EC #: 015-074-00-X
EINECS #: 206-083-1
    Formula: C12H19ClNO3P
Molecular mass: 291.7

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Liquid formulations containing organic solvents may be flammable.  NO open flames.  Use water spray, powder. 
EXPLOSION      
 
EXPOSURE   AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!   
Inhalation Dizziness. Sweating. Laboured breathing. Nausea. Unconciousness. Vomiting. Pupillary constriction, muscle cramp, excessive salivation.  Avoid inhalation of dust and mist. Use local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness. Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain.  Wear face shield or eye protection in combination with breathing protection if powder.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal cramps. Diarrhoea. Nausea. Vomiting. Pupillary constriction. Muscle cramps. Excessive salivation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT wash away into sewer.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: Xn, N; R: 21/22-50/53; S: (2)-36/37-60-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT7-III.  Separated from strong bases, strong acids and food and feedstuffs. Well closed. Keep in a well-ventilated room. 

IMPORTANT DATA
Physical State; Appearance
WHITE CRYSTALS. 

Physical dangers
No data. 

Chemical dangers
Decomposes on heating. This produces toxic and corrosive fumes including hydrogen chloride, nitrogen oxides and phosphorus oxides. Reacts with strong acids and strong bases. 

Occupational exposure limits
TLV: 5mg/m³ as TWA; A4 (not classifiable as a human carcinogen); BEI issued; (ACGIH 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the nervous system. This may result in convulsions and respiratory failure. Cholinesterase inhibition. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Decomposes at 60-65°C
Relative density (water = 1): 1.5
Solubility in water: none
Vapour pressure, Pa at 25°C: 0.106  
The substance is very toxic to aquatic organisms. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Carrier solvents used in commercial formulations may change physical and toxicological properties.
Do NOT take working clothes home.
Commercial product is a yellow oil.
Ruelene is a trade name.
Card has been partly updated in April 2005.
See sections Occupational Exposure Limits, Emergency Response. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Crufomate (FAO/PL:1968/M/9/1)
       Crufomate (WHO Pesticide Residues Series 2)