IPCS INCHEM Home
CRUFOMATEICSC: 1143
October 1995
CAS #: 299-86-54-tert-Butyl-2-chlorophenyl methyl methylphosphoramidate
Amidophos
UN #: 2783
EINECS #: 206-083-1

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Liquid formulations containing organic solvents may be flammable.    NO open flames.    Use water spray, powder.   

 AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!  
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation Dizziness. Sweating. Laboured breathing. Nausea. Unconsciousness. Vomiting. Pupillary constriction, muscle cramp, excessive salivation.  Avoid inhalation of dust and mist. Use local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness. Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain.  Wear face shield or eye protection in combination with breathing protection if powder.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal cramps. Diarrhoea. Nausea. Vomiting. Pupillary constriction. Muscle cramps. Excessive salivation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT wash away into sewer. 

According to UN GHS Criteria

 

Transportation
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 

STORAGE
Separated from strong bases, strong acids and food and feedstuffs. Well closed. Keep in a well-ventilated room. 
PACKAGING
Do not transport with food and feedstuffs. 
CRUFOMATE ICSC: 1143
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
WHITE CRYSTALS. 

Physical dangers
No data. 

Chemical dangers
Decomposes on heating. This produces toxic and corrosive fumes including hydrogen chloride, nitrogen oxides and phosphorus oxides. Reacts with strong acids and strong bases. 

Formula: C12H19ClNO3P
Molecular mass: 291.7
Decomposes at 60-65°C
Relative density (water = 1): 1.5
Solubility in water: none
Vapour pressure, Pa at 25°C: 0.106  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the nervous system. This may result in convulsions and respiratory failure. Cholinesterase inhibition. The effects may be delayed. Medical observation is indicated. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered. 

Effects of long-term or repeated exposure
 


Occupational exposure limits
TLV: 5 mg/m3, ppm, as TWA; A4 (not classifiable as a human carcinogen); BEI issued 

ENVIRONMENT
The substance is very toxic to aquatic organisms. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Carrier solvents used in commercial formulations may change physical and toxicological properties.
Do NOT take working clothes home.
Commercial product is a yellow oil. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: Xn, N; R: 21/22-50/53; S: (2)-36/37-60-61 

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    See Also:
       Toxicological Abbreviations
       Crufomate (FAO/PL:1968/M/9/1)
       Crufomate (WHO Pesticide Residues Series 2)