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4,4'-METHYLENEDIANILINE
ICSC: 1111
Peer-Review Status: 24.03.1999 Validated
4,4'-Diaminodiphenylmethane
4,4'-Methylenebisbenzenamine
MDA 
CAS #: 101-77-9 RTECS #: BY5425000
UN #: 2651
EC #: 612-051-00-1
EINECS #: 202-974-4
    Formula: C13H14N2 / NH2C6H4CH2C6H4NH2
Molecular mass: 198.3

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, powder, foam, carbon dioxide. 
EXPLOSION      
 
EXPOSURE   AVOID ALL CONTACT!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Abdominal pain. Nausea. Vomiting. Fever.  Use ventilation (not if powder), local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes   Wear safety spectacles or face shield.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Jaundice. Further see Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs.
Marine pollutant. 
EC Classification
Symbol: T, N; R: 45-39/23/24/25-43-48/20/21/22-68-51/53; S: 53-45-61; Note: E 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT2-III.
NFPA Code: H3; F1; R0. 
Separated from strong oxidants and food and feedstuffs. Well closed. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS-TO-PALE-YELLOW FLAKES WITH CHARACTERISTIC ODOUR. TURNS DARK ON EXPOSURE TO AIR. 

Physical dangers
 

Chemical dangers
Decomposes on heating and on burning. This produces toxic fumes including aniline and nitrogen oxides. The substance is a weak base. Reacts violently with strong oxidants. 

Occupational exposure limits
TLV: 0.1ppm as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2008).
MAK: Carcinogen category: 2; Skin absorption (H); Sensitization of skin (SH); (DFG 2008). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly. 

Effects of short-term exposure
The substance may cause effects on the liver. This may result in liver impairment. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. This substance is possibly carcinogenic to humans. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point at 102kPa: 398-399°C
Melting point: 91.5-92°C
Density: 0.5 g/cm³
Solubility in water: poor
Vapour pressure, Pa at 197°C: 133
Flash point: 220°C c.c.
Octanol/water partition coefficient as log Pow: 1.6  
The substance is harmful to aquatic organisms. It is strongly advised not to let the chemical enter into the environment. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Ancamine TL, Araldite hardener 972, Epicure DDM, Slumicure M, Tonox are trade names.
Card has been partly updated in October 2004. See sections Occupational Exposure Limits, EU classification, Emergency Response.
Card has been partially updated in November 2008: see Occupational Exposure Limits and Storage. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
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    See Also:
       Toxicological Abbreviations