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2,3,4,6-TETRACHLOROPHENOL
ICSC: 1089
Peer-Review Status: 20.10.2005 Validated
2,4,5,6-Tetrachlorophenol
Phenol, 2,3,4,6-tetrachloro- 
CAS #: 58-90-2 RTECS #: SM9275000
UN #: 2020
EC #: 604-013-00-8
EINECS #: 200-402-8
    Formula: C6H2Cl4O
Molecular mass: 231.9

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, alcohol-resistant foam, dry powder, carbon dioxide. 
EXPLOSION      
 
EXPOSURE   PREVENT DISPERSION OF DUST!   
Inhalation Cough. Shortness of breath. Convulsions.  Use local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain.  Wear safety goggles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Diarrhoea. Headache. Dizziness. Vomiting. Weakness. Convulsions. Muscle spasms. Fever. Sweating. See Notes.  Do not eat, drink, or smoke during work. Wash hands before eating.  Give a slurry of activated charcoal in water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: chemical protection suit and particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T, N; R: 25-36/38-50/53; S: (1/2)-26-28-37-45-60-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61S2020 or 61GT2-III.  Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
BROWN SOLID IN VARIOUS FORMS WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
Decomposes on heating. This produces corrosive fumes including hydrogen chloride. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):. 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Inhalation risk
A harmful concentration of airborne particles can be reached quickly when dispersed. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. See Notes. 

Effects of long-term or repeated exposure
The substance may have effects on the liver. The substance may have effects on the skin. This may result in chloracne. See Notes. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Melting point: 70°C
Density: 1.8 g/cm³
Solubility in water, g/100ml at 20°C: 0.1 (very poor)
Flash point: 100°C
Octanol/water partition coefficient as log Pow: 4.45  
The substance is very toxic to aquatic organisms. Bioaccumulation of this chemical may occur in fish. 

NOTES
2,3,4,6-Tetrachlorophenol is a polychlorophenol which, as a group, has been classified by IARC (1999) as possibly carcinogenic to humans, but the data on this specific substance are inconclusive.
No data are available on this isomer but a mixture of tetrachlorophenols may cause irritation of the skin, eyes and respiratory tract.
These substances may cause acute metabolic effects resulting in damage in several organs notably in central nervous system.
Some technical products may contain highly toxic impurities including polychlorinated dibenzo-p-dioxins and -furans.
Depending on the degree of exposure, periodic medical examination is suggested. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations