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METHYLACETOACETATE
ICSC: 1086
Peer-Review Status: 25.11.2003 Validated
Acetoacetic acid methyl ester
Butanoic acid, 3-oxo-, methyl ester
1-Methoxybutane-1,3-dione 
CAS #: 105-45-3 RTECS #: AK5775000
EC #: 607-137-00-0
EINECS #: 203-299-8
    Formula: C5H8O3
Molecular mass: 116.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible.  NO open flames.  Use alcohol-resistant foam, powder, carbon dioxide. 
EXPLOSION Above 77°C explosive vapour/air mixtures may be formed.  Above 77°C use a closed system and ventilation.   
 
EXPOSURE      
Inhalation Cough. Dizziness. Drowsiness. Headache. Sore throat.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin   Protective gloves.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness. Pain.  Wear safety goggles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion   Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Wash away remainder with plenty of water.   
EC Classification
Symbol: Xi; R: 36; S: (2)-26 
UN Classification
 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H2; F2; R0.  Separated from oxidants. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
Decomposes on burning. This produces irritating fumes. Reacts with oxidants. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):. 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour. 

Inhalation risk
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes and respiratory tract. Exposure could cause lowering of consciousness. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 171.7°C
Melting point: -27°C
Relative density (water = 1): 1.08
Solubility in water, g/100ml: 50
Vapour pressure, kPa at 20°C: 0.17
Relative vapour density (air = 1): 4.0
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.01
Flash point: 77°C c.c.
Auto-ignition temperature: 280°C
Explosive limits, vol% in air: 1.4-14.5
Octanol/water partition coefficient as log Pow: -0.26  
 

NOTES
 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations