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ETHYL ACETOACETATE
ICSC: 1024
Peer-Review Status: 13.04.2000 Validated
Acetoacetic acid ethyl ester
Ethyl acetylacetate
3-Oxobutanoic acid ethyl ester
1-Ethoxybutane-1,3-dione 
CAS #: 141-97-9 RTECS #: AK5250000
EINECS #: 205-516-1
    Formula: C6H10O3 / CH3COCH2COOC2H5
Molecular mass: 130.14

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible.  NO open flames.  Use water spray, powder, foam, carbon dioxide. 
EXPLOSION Above 70°C explosive vapour/air mixtures may be formed.  Above 70°C use a closed system and ventilation.   
 
EXPOSURE   PREVENT GENERATION OF MISTS!   
Inhalation Cough. Sore throat.  Use ventilation.  Fresh air, rest. 
Skin Redness.  Protective gloves.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes Redness. Pain.  Wear safety spectacles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion   Do not eat, drink, or smoke during work.  Rinse mouth. Give one or two glasses of water to drink. Rest. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Wash away remainder with plenty of water.   
EC Classification
 
UN Classification
 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H2; F2; R0.  Separated from strong oxidants. Ventilation along the floor. Well closed. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air. 

Chemical dangers
Reacts with strong oxidants. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):. 

Routes of exposure
The substance can be absorbed into the body by inhalation. 

Inhalation risk
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 180.8°C
Melting point: -45°C
Relative density (water = 1): 1.021
Solubility in water, g/100ml at 20°C: 2.86
Vapour pressure, kPa at 20°C: 0.1
Relative vapour density (air = 1): 4.48
Flash point: 70°C c.c.
Auto-ignition temperature: 295°C
Explosive limits, vol% in air: 1-54
Octanol/water partition coefficient as log Pow: 0.27  
 

NOTES
Card has been partially updated in November 2008: see Occupational Exposure Limits, Ingestion First Aid. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.
    See Also:
       Toxicological Abbreviations
       ETHYL ACETOACETATE (JECFA Evaluation)