AZINPHOS-METHYL (ICSC)

AZINPHOS-METHYL	ICSC: 0826

Date of peer-review: March 1998

Phosphorodithioic acid 0,0-dimethyl S-((4-oxo-11,2,3-benzotriazin-3-(4H)-yl)methyl) ester
S-3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-ylmethyl) O,O-dimethyl phosphorodithioate

CAS #

86-50-0

C₁₀H₁₂N₃O₃PS₂

RTECS #

TE1925000

Molecular mass: 317.3

UN #

2783

EC #

015-039-00-9

TYPES OF HAZARD / EXPOSURE	ACUTE HAZARDS / SYMPTOMS	PREVENTION	FIRST AID / FIRE FIGHTING
FIRE	Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Powder, water spray, foam, carbon dioxide.
EXPLOSION

EXPOSURE		PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!	IN ALL CASES CONSULT A DOCTOR!
Inhalation	Headache. Pupillary constriction, muscle cramp, excessive salivation. Sweating. Nausea. Dizziness. Wheezing. Laboured breathing. Convulsions. Unconsciousness.	Ventilation (not if powder), local exhaust, or breathing protection.	Fresh air, rest. Artificial respiration if indicated. Refer for medical attention.
Skin	MAY BE ABSORBED! (See Inhalation).	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
Eyes	Blurred vision.	Face shield, or eye protection in combination with breathing protection if powder.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion	Abdominal cramps. Vomiting. Diarrhoea. Blurred vision. (Further see Inhalation).	Do not eat, drink, or smoke during work. Wash hands before eating.	Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.

SPILLAGE DISPOSAL

PACKAGING & LABELLING

Do NOT wash away into sewer. Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. (Extra personal protection: complete protective clothing including self-contained breathing apparatus).

Do not transport with food and feedstuffs. Severe marine pollutant.
EU Classification
Symbol: T+
R: 24-28
S: (1/2-)28-36/37-45
UN Classification
UN Hazard Class: 6.1
UN Pack Group: II

EMERGENCY RESPONSE

STORAGE

Transport Emergency Card: TEC (R)-61G41b

Separated from food and feedstuffs. Well closed.

IPCS
International
Programme on
Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities © IPCS, CEC 2001

SEE IMPORTANT INFORMATION ON BACK

AZINPHOS-METHYL

ICSC: 0826

IMPORTANT DATA

PHYSICAL STATE; APPEARANCE:
COLOURLESS CRYSTALS.

CHEMICAL DANGERS:
The substance decomposes on heating above 200°C and on burning producing toxic and corrosive fumes including nitrogen oxides, phosphorous oxides, sulfur oxides.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 0.2 mg/m^3 (skin) (ACGIH 1997). MAK: 0.2 mg/m^3; III, H (1996).

ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

INHALATION RISK:
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance may cause effects on the nervous system, resulting in convulsions, respiratory failure. Cholinesterase inhibitor. Exposure may result in unconsciousness or death. The effects may be delayed. Medical observation is indicated.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Cholinesterase inhibitor; cumulative effect is possible: see acute hazards/symptoms.

PHYSICAL PROPERTIES

Melting point: 73-74°C
Density: 1.4 g/cm^3
Solubility in water: none
Vapour pressure, Pa at 20°C: < 0.001

Octanol/water partition coefficient as log Pow: 2.75

ENVIRONMENTAL DATA

The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment; special attention should be given to honey bees. Avoid release to the environment in circumstances different to normal use.

NOTES

The technical material is a brown waxy solid. Depending on the degree of exposure, periodic medical examination is indicated. The symptoms of acute intoxication do not become manifest until 30 minutes to 1-2 hours. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s). Carrier solvents used in commercial formulations may change physical and toxicological properties. Do NOT take working clothes home. Guthion and Gusathion M are trade names.

ADDITIONAL INFORMATION

LEGAL NOTICE

Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information

    See Also:
       Toxicological Abbreviations
       Azinphos-methyl (PDS)
       Azinphos-Methyl (FAO Meeting Report PL/1965/10/1)
       Azinphos-methyl (FAO/PL:1968/M/9/1)
       Azinphos-methyl (WHO Pesticide Residues Series 2)
       Azinphos-methyl (WHO Pesticide Residues Series 3)
       Azinphos-methyl (WHO Pesticide Residues Series 4)
       Azinphos-methyl (Pesticide residues in food: 1991 evaluations Part II Toxicology)