ICSC 0826 - AZINPHOS-METHYL

AZINPHOS-METHYL

ICSC: 0826
_{Peer-Review Status: 26.03.1998 Validated}

Phosphorodithioic acid 0,0-dimethyl S-((4-oxo-11,2,3-benzotriazin-3-(4H)-yl)methyl) ester
S-3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-ylmethyl) O,O-dimethyl phosphorodithioate

CAS #: 86-50-0 RTECS #: TE1925000
UN #: 2783
EC #: 015-039-00-9
EINECS #: 201-676-1

Formula: C₁₀H₁₂N₃O₃PS₂
Molecular mass: 317.3

TYPES OF HAZARD / EXPOSURE	ACUTE HAZARDS / SYMPTOMS	PREVENTION	FIRST AID / FIRE FIGHTING
FIRE	Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Use water spray, powder, foam, carbon dioxide.
EXPLOSION

EXPOSURE		PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!	IN ALL CASES CONSULT A DOCTOR!
Inhalation	Headache. Pupillary constriction, muscle cramp, excessive salivation. Sweating. Nausea. Dizziness. Wheezing. Laboured breathing. Convulsions. Unconciousness.	Use ventilation (not if powder), local exhaust or breathing protection.	Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Skin	MAY BE ABSORBED! See Inhalation.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
Eyes	Blurred vision.	Wear face shield or eye protection in combination with breathing protection if powder.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Abdominal cramps. Vomiting. Diarrhoea. Blurred vision. Further see Inhalation.	Do not eat, drink, or smoke during work. Wash hands before eating.	Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention .

SPILLAGE DISPOSAL	PACKAGING & LABELLING
Do NOT wash away into sewer. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Personal protection: complete protective clothing including self-contained breathing apparatus.	Do not transport with food and feedstuffs. Severe marine pollutant. EC Classification Symbol: T+, N; R: 24-26/28-43-50/53; S: (1/2)-28-36/37-45-60-61 UN Classification UN Hazard Class: 6.1; UN Pack Group: II GHS Classification

EMERGENCY RESPONSE	SAFE STORAGE
Transport Emergency Card: TEC (R)-61G41B.	Separated from food and feedstuffs. Well closed.

IMPORTANT DATA

Physical State; Appearance
COLOURLESS CRYSTALS.

Physical dangers

Chemical dangers
Decomposes above 200°C . Decomposes on burning. This produces toxic and corrosive fumes including nitrogen oxides, phosphorus oxides and sulfur oxides.

Occupational exposure limits
MAK (inhalable fraction): 0.2 mg/m³; Peak limitation category: II(8); Skin absorption (H); (DFG 2007).

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered.

Effects of short-term exposure
The substance may cause effects on the nervous system. This may result in convulsions and respiratory failure. Cholinesterase inhibition. Exposure could cause unconsciousness and death. The effects may be delayed. Medical observation is indicated.

Effects of long-term or repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.

PHYSICAL PROPERTIES	ENVIRONMENTAL DATA
Melting point: 73-74°C Density: 1.4 g/cm³ Solubility in water: none Vapour pressure, Pa at 20°C: <0.001 Octanol/water partition coefficient as log Pow: 2.75	The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to bees. Avoid release to the environment in circumstances different to normal use.

NOTES

The technical material is a brown waxy solid.
Depending on the degree of exposure, periodic medical examination is indicated.
The symptoms of acute intoxication do not become manifest until 30 minutes to 1-2 hours.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s).
Carrier solvents used in commercial formulations may change physical and toxicological properties.
Do NOT take working clothes home.
Guthion and Gusathion M are trade names.
Card has been partially updated in March 2008: see Occupational Exposure Limit, Packaging & labelling.

ADDITIONAL INFORMATION

IPCS
International
Programme on
Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012

LEGAL NOTICE

Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.

    See Also:
       Toxicological Abbreviations
       Azinphos-methyl (PDS)
       Azinphos-Methyl (FAO Meeting Report PL/1965/10/1)
       Azinphos-methyl (FAO/PL:1968/M/9/1)
       Azinphos-methyl (WHO Pesticide Residues Series 2)
       Azinphos-methyl (WHO Pesticide Residues Series 3)
       Azinphos-methyl (WHO Pesticide Residues Series 4)
       Azinphos-methyl (Pesticide residues in food: 1991 evaluations Part II Toxicology)