IPCS INCHEM Home
METHYL ISOAMYL KETONE
ICSC: 0815
Peer-Review Status: 26.03.1998 Validated
5-Methylhexan-2-one
MIAK
2-Methyl-5-hexanone 
CAS #: 110-12-3 RTECS #: MP3850000
UN #: 2302
EC #: 606-026-00-4
EINECS #: 203-737-8
    Formula: C7H14O / CH3CO(CH2)2CH(CH3)2
Molecular mass: 114.2

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Flammable.  NO open flames, NO sparks and NO smoking.  Use AFFF, alcohol-resistant foam, powder, carbon dioxide. 
EXPLOSION Above 36°C explosive vapour/air mixtures may be formed.  Above 36°C use a closed system, ventilation and explosion-proof electrical equipment.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE      
Inhalation Cough. Headache. Dizziness. Drowsiness. Laboured breathing. Sore throat.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Dry skin. Redness.  Protective gloves. Protective clothing.  First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Refer for medical attention . 
Eyes Redness.  Wear safety spectacles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Nausea. See Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer.   
EC Classification
Symbol: Xn; R: 10-20; S: (2)-23-24/25 
UN Classification
UN Hazard Class: 3; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-30S2302.
NFPA Code: H1; F2; R0. 
Fireproof. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour mixes well with air, explosive mixtures are easily formed. 

Chemical dangers
Reacts violently with strong oxidants, strong bases, amines and isocyanates. This generates fire and explosion hazard. Attacks some plastics. 

Occupational exposure limits
TLV: 50ppm as TWA; (ACGIH 2004).
MAK: 10 ppm, 47 mg/m³; Peak limitation category: I(2); Pregnancy risk group: D; (DFG 2007). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour. 

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the kidneys. This may result in kidney impairment. Exposure above the OEL could cause lowering of consciousness. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 144°C
Melting point: -74°C
Relative density (water = 1): 0.89
Solubility in water, g/100ml at 20°C: 0.5 (poor)
Vapour pressure, kPa at 20°C: 0.6
Relative vapour density (air = 1): 3.9
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.02
Flash point: 36°C c.c.
Auto-ignition temperature: 191°C
Explosive limits, vol% in air: 1.0-8.2 (at 93°C)
Octanol/water partition coefficient as log Pow: 1.72 (estimated) 
 

NOTES
Card has been partly updated in October 2004 and 2005. See sections Occupational Exposure Limits, EU classification, Emergency Response.
Card has been partially updated in March 08: see Occupational Exposure Limits. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations