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CHLOROACETONE
ICSC: 0760
Peer-Review Status: 11.10.2006 Validated
1-Chloro-2-propanone
Acetonyl chloride
Monochloroacetone 
CAS #: 78-95-5 RTECS #: UC0700000
UN #: 1695 (stabilized)
EINECS #: 201-161-1
    Formula: C3H5ClO / ClCH2COCH3
Molecular mass: 92.5

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Flammable. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking.  Use water spray, powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION Above 35°C explosive vapour/air mixtures may be formed.  Above 35°C use a closed system, ventilation and explosion-proof electrical equipment.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   STRICT HYGIENE!   
Inhalation Sore throat. Cough. Burning sensation. Shortness of breath. See Notes.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness. Pain. Blisters. See Notes.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Redness. Watering of the eyes. Pain. Burns.  Wear face shield or eye protection in combination with breathing protection.  Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Blue haze and halo. 
Ingestion Burning sensation in the throat and chest.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Remove all ignition sources. Evacuate danger area! Consult an expert! Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Collect leaking liquid in covered containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Unbreakable packaging.
Put breakable packaging into closed unbreakable container.
Do not transport with food and feedstuffs. 
EC Classification
 
UN Classification
UN Hazard Class: 6.1; UN Subsidiary Risks: 3 and 8; UN Pack Group: I 
GHS Classification
Signal: Danger
Flammable liquid and vapour
Toxic if swallowed
Fatal in contact with skin
Fatal if inhaled vapour
Causes skin irritation
Causes serious eye damage
May cause respiratory irritation 
flam;flameskull;toxiccorr

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GTFC-I.  Store only if stabilized. Fireproof. Separated from strong oxidants and food and feedstuffs. Keep in the dark. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH PUNGENT ODOUR. TURNS DARK ON EXPOSURE TO LIGHT. 

Physical dangers
 

Chemical dangers
The substance slowly polymerizes under the influence of light. This generates fire or explosion hazard. Decomposes on heating and on burning. 

Occupational exposure limits
TLV: 1ppm (ceiling value); (skin); (ACGIH 2006). 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
Lachrymation. The substance is severely irritating to the eyes, skin and respiratory tract. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 120°C
Melting point: -45°C
Relative density (water = 1): 1.1
Solubility in water, g/100ml at 20°C: 10
Vapour pressure, kPa at 25°C: 1.5
Relative vapour density (air = 1): 3.2
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.03
Flash point: 35 °C c.c.
Auto-ignition temperature: 610 °C
Explosive limits, vol% in air: 3.4-?
Octanol/water partition coefficient as log Pow: 0.28  
 

NOTES
After contact with liquid blister formation may be delayed until several hours have passed.
Explosive limits are unknown in literature, although the substance is combustible and has a flash point < 55°C.
The occupational exposure limit value should not be exceeded during any part of the working exposure.
The odour warning when the exposure limit value is exceeded is insufficient.
An added stabilizer or inhibitor can influence the toxicological properties of this substance, consult an expert.
Card has been partially updated in March 2009: see GHS classification. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.
    See Also:
       Toxicological Abbreviations