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TRICHLORONITROMETHANE
ICSC: 0750
Peer-Review Status: 24.11.1998 Validated
Chloropicrin
Nitrochloroform
Nitrotrichloromethane 
CAS #: 76-06-2 RTECS #: PB6300000
UN #: 1580
EC #: 610-001-00-3
EINECS #: 200-930-9
    Formula: CCl3NO2
Molecular mass: 164.4

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Not combustible. Many reactions may cause fire or explosion.    In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION      
 
EXPOSURE   STRICT HYGIENE!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Abdominal pain. Cough. Diarrhoea. Dizziness. Headache. Nausea. Sore throat. Vomiting. Weakness. Symptoms may be delayed. See Notes.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Refer for medical attention. 
Skin Redness. Pain.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain. Blurred vision.  Wear safety spectacles, face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Personal protection: chemical protection suit including self-contained breathing apparatus.  Unbreakable packaging.
Put breakable packaging into closed unbreakable container.
Do not transport with food and feedstuffs. 
EC Classification
Symbol: T+; R: 22-26-36/37/38; S: (1/2)-36/37-38-45 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: I 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-162.
NFPA Code: H4; F0; R3. 
Separated from food and feedstuffs. See Chemical Dangers. Cooled. Keep in the dark. Ventilation along the floor. 

IMPORTANT DATA
Physical State; Appearance
SLIGHTLY OILY COLOURLESS LIQUID WITH PUNGENT ODOUR. 

Physical dangers
The vapour is heavier than air. 

Chemical dangers
May explode on heating or on shock. Decomposes on heating and under the influence of light. This produces toxic fumes including hydrogen chloride and nitrogen oxides. Reacts violently with alcoholic sodium hydroxide, sodium methoxide, propargyl bromide and heated aniline. 

Occupational exposure limits
TLV: 0.1ppm, 0.67mg/m³ as TWA; A4 (not classifiable as a human carcinogen); (ACGIH 1998).
MAK: 0.1 ppm, 0.68 mg/m³; Peak limitation category: I(1); (DFG 2006). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
Lachrymation. The substance is severely irritating to the eyes, skin and respiratory tract. Inhalation of the vapour may cause lung oedema. See Notes. Exposure above the OEL could cause death. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 112°C
Melting point: -64°C
Relative density (water = 1): 1.7
Solubility in water, g/100ml at 25°C: 0.162
Vapour pressure, kPa at 20°C: 2.7
Relative vapour density (air = 1): 5.7
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.12
Octanol/water partition coefficient as log Pow: 2.1  
 

NOTES
Depending on the degree of exposure, periodic medical examination is indicated.
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation is therefore essential.
Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered.
The odour warning when the exposure limit value is exceeded is insufficient.
Do NOT take working clothes home.
Card has been partially updated in August 2007: see Ingestion First Aid, Occupational Exposure Limits. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations