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DEMETON-S-METHYLICSC: 0705
August 1997
CAS #: 919-86-8S-2-Ethylthioethyl O,O-dimethyl phosphorothioate
Phosphorothioic acid, S-(2-(ethylthio)ethyl)O,O-dimethyl ester
UN #: 3018
EINECS #: 213-052-6

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.  Risk of fire and explosion if formulations contain flammable/explosive solvents.  NO open flames.    Use water spray, foam, powder, carbon dioxide.   

 PREVENT GENERATION OF MISTS! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN! IN ALL CASES CONSULT A DOCTOR! 
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation Pupillary constriction, muscle cramp, excessive salivation. Sweating. Nausea. Vomiting. Abdominal cramps. Diarrhoea. Unconsciousness. Dizziness. Laboured breathing. Weakness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Pupillary constriction. Blurred vision.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Convulsions. Further see Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Give a slurry of activated charcoal in water to drink. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Rest. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer. 

According to UN GHS Criteria

 

Transportation
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 

STORAGE
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Keep in a well-ventilated room. 
PACKAGING
Do not transport with food and feedstuffs. 
DEMETON-S-METHYL ICSC: 0705
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS-TO-PALE YELLOW OILY LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
Decomposes on heating and on burning. This produces toxic fumes including phosphorus oxides and sulfur oxides. 

Formula: C6H15O3PS2 / (CH3O)2P(O)SCH2CH2SCH2CH3
Molecular mass: 230.3
Boiling point at 0.13kPa: 118°C
Relative density (water = 1): 1.2
Solubility in water, g/100ml at 20°C: 0.33
Vapour pressure, Pa at 20°C: 0.048
Relative vapour density (air = 1): 7.9
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Octanol/water partition coefficient as log Pow: 1.32  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. 

Effects of short-term exposure
The substance may cause effects on the nervous system. This may result in convulsions, respiratory failure and death. Cholinesterase inhibition. The effects may be delayed. Medical observation is indicated. 

Inhalation risk
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. 

Effects of long-term or repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms. 


Occupational exposure limits
TLV: 0.05 mg/m3, ppm, as TWA; (skin); (SEN); A4 (not classifiable as a human carcinogen).
TLV BEI issued 

ENVIRONMENT
The substance is toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to bees, mammals and birds. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
If the substance is formulated with solvents also consult the ICSCs of these materials.
Carrier solvents used in commercial formulations may change physical and toxicological properties.
Do NOT take working clothes home.
Also consult ICSC 0429 (Demeton-O-methyl). 

ADDITIONAL INFORMATION
  EC Classification
Symbol: T, N; R: 24/25-51/53; S: (1/2)-28-36/37-45-61 

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    See Also:
       Toxicological Abbreviations
       Demeton-s-methyl (EHC 197, 1997)
       Demeton-s-methyl (Pesticide residues in food: 1979 evaluations)
       Demeton-S-methyl (Pesticide residues in food: 1984 evaluations)