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BISPHENOL A
ICSC: 0634
Peer-Review Status: 09.06.2011 Validated
4,4'-(1-Methylethylidene)bisphenol
4,4'-Isopropylidenediphenol 
CAS #: 80-05-7 RTECS #: SL6300000
EC #: 604-030-00-0
EINECS #: 201-245-8
 		    Formula: C15H16O2 / (CH3)2C(C6H4OH)2
Molecular mass: 228.3

TYPES OF
HAZARD /
EXPOSURE 		ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible.  NO open flames.  Use water spray, foam, powder, carbon dioxide. 
EXPLOSION Finely dispersed particles form explosive mixtures in air.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent deposition of dust.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE See EFFECTS OF LONG-TERM OR REPEATED EXPOSURE.  PREVENT DISPERSION OF DUST! AVOID ALL CONTACT!   
Inhalation Cough. Sore throat.  Use local exhaust or breathing protection.  Fresh air, rest. Seek medical attention if you feel unwell. 
Skin Redness.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Seek medical attention if you feel unwell. 
Eyes Redness. Pain.  Wear safety goggles or face shield.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Nausea.  Do not eat, drink, or smoke during work.  Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
 		PACKAGING & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.   
EC Classification
Symbol: Xn; R: 37-41-43-52-62; S: (2)-26-36/37-39-46-61 
UN Classification
 
GHS Classification
Signal: Warning
Causes serious eye irritation
May cause an allergic skin reaction
Suspected of damaging fertility or the unborn child
May cause respiratory irritation
Toxic to aquatic life 
excl mark;warncancer;health haz

EMERGENCY RESPONSE SAFE STORAGE
  Separated from acid anhydrides, acid chlorides, strong oxidants, strong bases and food and feedstuffs. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
WHITE CRYSTALS FLAKES OR POWDER. 

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air. 

Chemical dangers
Reacts violently with strong oxidants. This generates fire and explosion hazard. Reacts vigorously with acid anhydrides, acid chlorides and strong bases. This generates heat and pressure-rise explosion hazard. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):.
MAK (inhalable fraction): 5 mg/m³; Peak limitation category: I(1); Pregnancy risk group: C; Photosentization (SP); BAT issued; (DFG 2010).
EU OEL (inhalable fraction selected): 10mg/m³ as TWA;. 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol. 

Inhalation risk
Evaporation at 20°C is negligible; a nuisance-causing concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered. 

Effects of short-term exposure
The substance is severely irritating to the eyes. The substance is mildly irritating to the respiratory tract. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization and photosensitization. The substance may have effects on the upper respiratory tract. Ingestion may cause effects on the liver and kidneys. Animal tests show that this substance possibly causes toxic effects upon human reproduction. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point at 1.7kPa: 250-252°C
Melting point: 150-157°C
Relative density (water = 1): 1.2 (25°C)
Solubility in water, g/100ml: 0.03 (very poor)
Vapour pressure, Pa at 25°C: negligible
Flash point: 227°C c.c.
Auto-ignition temperature: 510-570°C
Octanol/water partition coefficient as log Pow: 3.32   		The substance is toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment. 

NOTES
The substance is absorbed through the skin but no toxic effects were reported (2011) 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety 		WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
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       Toxicological Abbreviations