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2,4-PENTADIONE
ICSC: 0533
Peer-Review Status: 04.08.1997 Validated
Acetyl 2-propanone
Acetoacetone
Acetyl acetone
Pentane-2,4-dione 
CAS #: 123-54-6 RTECS #: SA1925000
UN #: 2310
EC #: 606-029-00-0
EINECS #: 204-634-0
    Formula: C5H8O2 / CH3COCH2COCH3
Molecular mass: 100.13

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Flammable.  NO open flames, NO sparks and NO smoking.  Use powder, foam, carbon dioxide. 
EXPLOSION Above 34°C explosive vapour/air mixtures may be formed.  Above 34°C use a closed system, ventilation and explosion-proof electrical equipment.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   STRICT HYGIENE!   
Inhalation Incoordination. Dizziness. Drowsiness. Headache. Laboured breathing. Nausea. Vomiting.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes Redness. Pain.  Wear safety goggles or face shield.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Diarrhoea. Weakness. Further see Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Ventilation. Collect leaking liquid in sealable containers. Wash away remainder with plenty of water.   
EC Classification
Symbol: Xn; R: 10-22; S: (2)-21-23-24/25 
UN Classification
UN Hazard Class: 3; UN Subsidiary Risks: 6.1; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H2; F2; R0.  Fireproof. Separated from strong oxidants. Keep in the dark. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air. 

Chemical dangers
The substance may polymerize under the influence of light. Reacts with strong oxidants, bases and reducing agents. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):.
MAK: 20 ppm, 83 mg/m³; Peak limitation category: II(2); Pregnancy risk group: C; Skin absorption (H); (DFG 2006). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. 

Inhalation risk
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the nervous system. This may result in tissue lesions. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the thymus, lungs, central nervous system and nasal passage. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 140°C
Melting point: -23°C
Relative density (water = 1): 0.98
Solubility in water, g/100ml: 16
Vapour pressure, kPa at 20°C: 0.93
Relative vapour density (air = 1): 3.45
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.02
Flash point: 34°C c.c.
Auto-ignition temperature: 340°C
Explosive limits, vol% in air: 2.4-11.6 
The substance is harmful to aquatic organisms. 

NOTES
Card has been partially updated in August 2007: see Fire fighting, Occupational Exposure Limits. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations