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ISOBUTYL ACETATE
ICSC: 0494
Peer-Review Status: 26.11.2003 Validated
2-Methylpropyl acetate
2-Methyl-1-propyl acetate
Acetic acid, 2-methylpropyl ester
beta-Methylpropyl ethanoate 
CAS #: 110-19-0 RTECS #: AI4025000
UN #: 1213
EC #: 607-026-00-7
EINECS #: 203-745-1
    Formula: C6H12O2 / CH3COOCH2CH(CH3)2
Molecular mass: 116.16

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Highly flammable.  NO open flames, NO sparks and NO smoking.  Use foam, alcohol-resistant foam, dry powder, carbon dioxide. 
EXPLOSION Vapour/air mixtures are explosive.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE      
Inhalation Cough. Sore throat. Dizziness. Headache.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Dry skin.  Protective gloves.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes Redness.  Wear safety spectacles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Nausea.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Remove all ignition sources. Do NOT wash away into sewer. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.   
EC Classification
Symbol: F; R: 11-66; S: (2)-16-23-25-29-33; Note: C 
UN Classification
UN Hazard Class: 3; UN Pack Group: II 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-30S1213.
NFPA Code: H1; F3; R0. 
Fireproof. Separated from strong oxidants, strong bases and strong acids. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour mixes well with air, explosive mixtures are easily formed. 

Chemical dangers
Reacts with strong oxidants, strong acids and strong bases. This generates fire and explosion hazard. 

Occupational exposure limits
TLV: 150ppm as TWA; (ACGIH 2003).
MAK: 100 ppm, 480 mg/m³; Peak limitation category: I(2); Pregnancy risk group: C; (DFG 2003). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour. 

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The vapour is mildly irritating to the eyes and respiratory tract. The substance may cause effects on the central nervous system. Exposure far above the OEL could cause lowering of consciousness. 

Effects of long-term or repeated exposure
The liquid defats the skin. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 118°C
Melting point: -99°C
Relative density (water = 1): 0.87
Solubility in water, g/100ml at 20°C: 0.67
Vapour pressure, kPa at 20°C: 1.73
Relative vapour density (air = 1): 4.0
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.05
Flash point: 18°C c.c.
Auto-ignition temperature: 421°C
Explosive limits, vol% in air: 1.3-10.5
Octanol/water partition coefficient as log Pow: 1.60  
 

NOTES
 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       ISOBUTYL ACETATE (JECFA Evaluation)