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2-HEXANONE
ICSC: 0489
Peer-Review Status: 24.11.1998 Validated
Methyl n-butyl ketone
n-Butyl methyl ketone
MBK 
CAS #: 591-78-6 RTECS #: MP1400000
UN #: 1224
EC #: 606-030-00-6
EINECS #: 209-731-1
    Formula: C6H12O / C4H9COCH3
Molecular mass: 100.2

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Flammable.  NO open flames, NO sparks and NO smoking.  Use alcohol-resistant foam, powder, carbon dioxide. 
EXPLOSION Above 23°C explosive vapour/air mixtures may be formed.  Above 23°C use a closed system, ventilation and explosion-proof electrical equipment.  In case of fire: keep cylinder cool by spraying with water. 
 
EXPOSURE      
Inhalation Cough. Drowsiness. Headache. Nausea. Sore throat.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Dry skin.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain. Blurred vision.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Diarrhoea. Sore throat. Further see Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: self-contained breathing apparatus. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Note: 6 
EC Classification
Symbol: T; R: 10-48/23-62-67; S: (1/2)-36/37-45 
UN Classification
UN Hazard Class: 3; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-30G35.
NFPA Code: H2; F3; R0. 
Fireproof. Separated from strong oxidants. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
Reacts violently with oxidants. This generates fire and explosion hazard. Attacks plastics. 

Occupational exposure limits
TLV: 5 ppm as TWA; 10 ppm as STEL; (skin); BEI issued; (ACGIH 2006).
MAK: 5 ppm, 21 mg/m³; Peak limitation category: II(8); Skin absorption (H); (DFG 2006). 

Routes of exposure
The substance can be absorbed into the body by inhalation and through the skin. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C ; on spraying or dispersing much faster. 

Effects of short-term exposure
The substance is irritating to the eyes and respiratory tract. The substance may cause effects on the nervous system. Exposure far above the OEL could cause unconsciousness. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the nervous system. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 126-128°C
Melting point: -57°C
Relative density (water = 1): 0.8
Solubility in water, g/100ml at 20°C: 1.4
Vapour pressure, kPa at 20°C: 0.36
Relative vapour density (air = 1): 3.5
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.01
Flash point: 23°C c.c.
Auto-ignition temperature: 423°C
Explosive limits, vol% in air: 1.2-8.0
Octanol/water partition coefficient as log Pow: 1.38  
 

NOTES
Use of alcoholic beverages enhances the harmful effect.
MBK potentiates the toxicity of some other chemical substances like chloroform, carbon tetrachloride, ethanol.
Depending on the degree of exposure, periodic medical examination is indicated.
Card has been partially updated in July 2007: see Occupational Exposure Limits, EU Classification, Fire fighting. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations