IPCS INCHEM Home
DIISOPROPYLAMINEICSC: 0449
DIPA
N-(1-Methylethyl)-2-propanamine
July 1997
CAS #: 108-18-9
UN #: 1158
EC Number: 203-558-5

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.  Vapour/air mixtures are explosive.  NO open flames, NO sparks and NO smoking. NO contact with oxidizing agents.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent build-up of electrostatic charges (e.g., by grounding).  Use water spray, powder, alcohol-resistant foam, carbon dioxide.  In case of fire: keep drums, etc., cool by spraying with water. 

 PREVENT GENERATION OF MISTS! STRICT HYGIENE!  
  SYMPTOMS PREVENTION FIRST AID
Inhalation Burning sensation. Cough. Headache. Nausea. Shortness of breath. Symptoms may be delayed. See Notes.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. 
Skin MAY BE ABSORBED! Pain. Blisters.  Protective clothing.  First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Refer for medical attention . 
Eyes Redness. Pain. Blurred vision. Severe deep burns.  Wear safety spectacles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal cramps. Burning sensation. Nausea. Shock or collapse. Sore throat.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Wash away remainder with plenty of water. Do NOT wash away into sewer. 

According to UN GHS Criteria

 

Transportation
UN Classification
UN Hazard Class: 3; UN Subsidiary Risks: 8; UN Pack Group: II 

STORAGE
Separated from strong oxidants and strong acids. Cool. Well closed. Keep in a well-ventilated room. 
PACKAGING
 
DIISOPROPYLAMINE ICSC: 0449
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. 

Chemical dangers
Decomposes on heating. This produces toxic fumes of nitrogen oxides. The substance is a strong base. It reacts with acid and is corrosive. Reacts with oxidants. This generates fire and explosion hazard. Attacks some forms of plastic. 

Formula: C6H15N / CH3CH(CH3)NHCH(CH3)CH3
Molecular mass: 101.2
Boiling point: 84°C
Melting point: -61°C
See Notes.
Relative density (water = 1): 0.72
Solubility in water: none
Vapour pressure, kPa at 20°C: 9.3
Relative vapour density (air = 1): 3.5
Flash point: -6°C o.c.
Auto-ignition temperature: 316°C
Explosive limits, vol% in air: 0.8-7.1
Octanol/water partition coefficient as log Pow: 1.64  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. 

Effects of short-term exposure
Lachrymation. The vapour is corrosive to the eyes and respiratory tract. Inhalation of the vapour may cause lung oedema. See Notes. Contact of the vapour with the eyes may cause visual disturbances. Exposure could cause death. The effects may be delayed. Medical observation is indicated. 

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. 


OCCUPATIONAL EXPOSURE LIMITS
TLV: 5 ppm as TWA; (skin) 

ENVIRONMENT
The substance is harmful to aquatic organisms. 

NOTES
Other reported melting points: -91°C and -96°C.
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation are therefore essential.
Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: F, C; R: 11-20/22-34; S: (1/2)-16-26-36/37/39-45 

All rights reserved. The published material is being distributed without warranty of any kind, either expressed or implied. Neither ILO nor WHO nor the European Commission shall be responsible for the interpretation and use of the information contained in this material.
    See Also:
       Toxicological Abbreviations