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CYCLOHEXANONE
ICSC: 0425
Peer-Review Status: 21.04.2004 Validated
Ketohexamethylene
Pimelic ketone
Cyclohexyl ketone 
CAS #: 108-94-1 RTECS #: GW1050000
UN #: 1915
EC #: 606-010-00-7
EINECS #: 203-631-1
    Formula: C6H10O
Molecular mass: 98.14

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Flammable.  NO open flames, NO sparks and NO smoking.  Use alcohol-resistant foam, carbon dioxide, powder. 
EXPLOSION Above 44°C explosive vapour/air mixtures may be formed.  Above 44°C use a closed system, ventilation and explosion-proof electrical equipment. Prevent build-up of electrostatic charges (e.g., by grounding).  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE      
Inhalation Cough. Sore throat. Dizziness. Drowsiness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Dry skin. Redness.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Redness. Pain.  Wear safety goggles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Burning sensation.  Do not eat, drink, or smoke during work.  Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: chemical protection suit and filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Remove all ignition sources. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.   
EC Classification
Symbol: Xn; R: 10-20; S: (2)-25 
UN Classification
UN Hazard Class: 3; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-30S1915.
NFPA Code: H1; F2; R0. 
Fireproof. Separated from strong oxidants. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS OILY LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air. As a result of flow, agitation, etc., electrostatic charges can be generated. 

Chemical dangers
Reacts with strong oxidants such as nitric acid. This generates fire and explosion hazard. 

Occupational exposure limits
TLV: 20 ppm as TWA; 50 ppm as STEL; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance and the vapour are irritating to the eyes, skin and respiratory tract. Exposure far above the OEL could cause lowering of consciousness. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 156°C
Melting point: -32.1°C
Relative density (water = 1): 0.95
Solubility in water, g/100ml at 20°C: 8.7
Vapour pressure, Pa at 20°C: 500
Relative vapour density (air = 1): 3.4
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.01
Flash point: 44°C c.c.
Auto-ignition temperature: 420°C
Explosive limits, vol% in air: 1.1-9.4 (at 100°C)
Octanol/water partition coefficient as log Pow: 0.81
Electrical conductivity: 50000 pS/m  
 

NOTES
Card has been partially updated in July 2007: see Occupational Exposure Limits, Ingestion First Aid, Spillage Disposal. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       CYCLOHEXANONE (JECFA Evaluation)
       Cyclohexanone  (SIDS)
       Cyclohexanone  (IARC Summary & Evaluation, Volume 47, 1989)
       Cyclohexanone  (IARC Summary & Evaluation, Volume 71, 1999)