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DIETHYL ETHER
ICSC: 0355
Peer-Review Status: 03.05.2002 Validated
Ethyl ether
Ethyl oxide
Ether 
CAS #: 60-29-7 RTECS #: KI5775000
UN #: 1155
EC #: 603-022-00-4
EINECS #: 200-467-2
    Formula: C4H10O / (C2H5)2O
Molecular mass: 74.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Extremely flammable.  NO open flames, NO sparks and NO smoking. NO contact with hot surfaces.  Use alcohol-resistant foam, powder, carbon dioxide. 
EXPLOSION Vapour/air mixtures are explosive.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent build-up of electrostatic charges (e.g., by grounding). Do NOT use compressed air for filling, discharging, or handling. Use non-sparking handtools.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE      
Inhalation Cough. Sore throat. Drowsiness. Vomiting. Headache. Laboured breathing. Unconciousness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. 
Skin Dry skin.  Protective gloves.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness. Pain.  Wear safety goggles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Dizziness. Drowsiness. Vomiting.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Remove all ignition sources. Evacuate danger area! Consult an expert! Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Airtight. 
EC Classification
Symbol: F+, Xn; R: 12-19-22-66-67; S: (2)-9-16-29-33; Note: 6 
UN Classification
UN Hazard Class: 3; UN Pack Group: I 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-30S1155.
NFPA Code: H1; F4; R1. 
Fireproof. Separated from strong oxidants. See Chemical Dangers. Cool. Keep in the dark. Store only if stabilized. 

IMPORTANT DATA
Physical State; Appearance
VERY VOLATILE COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. As a result of flow, agitation, etc., electrostatic charges can be generated. 

Chemical dangers
The substance can form explosive peroxides under the influence of light and air. Reacts violently with halogens, interhalogens, sulfur compounds and oxidants. This generates fire and explosion hazard. Attacks plastics and rubber. 

Occupational exposure limits
TLV: 400 ppm as TWA; 500 ppm as STEL; (ACGIH 2001). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes and respiratory tract. If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis. The substance may cause effects on the central nervous system. This may result in narcosis. 

Effects of long-term or repeated exposure
The liquid defats the skin. The substance may have effects on the central nervous system. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 35°C
Melting point: -116°C
Relative density (water = 1): 0.7
Solubility in water, g/100ml at 20°C: 6.9
Vapour pressure, kPa at 20°C: 58.6
Relative vapour density (air = 1): 2.6
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.9
Flash point: -45°C c.c.
Auto-ignition temperature: 160-180°C
Explosive limits, vol% in air: 1.7-48
Octanol/water partition coefficient as log Pow: 0.89  
 

NOTES
Use of alcoholic beverages enhances the harmful effect.
Check for peroxides prior to distillation; eliminate if found.
Card has been partly updated in October 2004.
See sections Occupational Exposure Limits, EU classification, Emergency Response.
Card has been partially updated in January 2008: see Ingestion First Aid, Occupational Exposure Limits. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.
    See Also:
       Toxicological Abbreviations
       DIETHYL ETHER (JECFA Evaluation)