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PYRIDINEICSC: 0323
Azine
Azabenzene
December 2000
CAS #: 110-86-1
UN #: 1282
EC Number: 203-809-9

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.  Vapour/air mixtures are explosive.  NO open flames, NO sparks and NO smoking.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling.  Use water in large amounts, powder, alcohol-resistant foam, carbon dioxide.  In case of fire: keep drums, etc., cool by spraying with water. 

   
  SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Dizziness. Headache. Nausea. Shortness of breath. Unconsciousness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness. Burning sensation. Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Redness. Pain.  Wear safety spectacles or face shield.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Diarrhoea. Vomiting. Weakness. Further see Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: self-contained breathing apparatus. Remove all ignition sources. Do NOT wash away into sewer. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

 

Transportation
UN Classification
UN Hazard Class: 3; UN Pack Group: II 

STORAGE
Fireproof. Separated from strong oxidants and strong acids. Cool. Dry. Well closed. 
PACKAGING
 
PYRIDINE ICSC: 0323
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. 

Chemical dangers
Decomposes on burning. This produces toxic fumes of nitrogen oxides and hydrogen cyanide. The substance is a weak base. Reacts violently with strong oxidants and strong acids. 

Formula: C5H5N
Molecular mass: 79.1
Boiling point: 115°C
Melting point: -42°C
Relative density (water = 1): 0.98
Solubility in water: miscible
Vapour pressure, kPa at 20°C: 2.0
Relative vapour density (air = 1): 2.73
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.03
Flash point: 20°C c.c.
Auto-ignition temperature: 482°C
Explosive limits, vol% in air: 1.8-12.4
Octanol/water partition coefficient as log Pow: 0.65  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system and gastrointestinal tract. Exposure far above the OEL could cause lowering of consciousness. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of long-term or repeated exposure
The substance may have effects on the central nervous system, liver and kidneys. 


OCCUPATIONAL EXPOSURE LIMITS
TLV: 1 ppm as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans).
MAK: skin absorption (H); carcinogen category: 3B 

ENVIRONMENT
The substance is harmful to aquatic organisms. 

NOTES
Pyridine can normally be detected by odour at levels well below the TLV.
However, perception of the odour may decline quickly.
Depending on the degree of exposure, periodic medical examination is suggested. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: F, Xn; R: 11-20/21/22; S: (2)-26-28 

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    See Also:
       Toxicological Abbreviations
       Pyridine  (IARC Summary & Evaluation, Volume 77, 2000)