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PROPYLENE GLYCOL
ICSC: 0321
Peer-Review Status: 10.07.1997 Validated
1,2-Propanediol
Methyl ethylene glycol
1,2-Dihydroxypropane 
CAS #: 57-55-6 RTECS #: TY2000000
EINECS #: 200-338-0
    Formula: C3H8O2 / CH3CHOHCH2OH
Molecular mass: 76.09

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible.  NO open flames.  Use water spray, powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION Above 99°C explosive vapour/air mixtures may be formed.  Above 99°C use a closed system and ventilation.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   STRICT HYGIENE!   
Inhalation   Use ventilation.  Fresh air, rest. 
Skin   Protective gloves.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness. Pain.  Wear safety spectacles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion   Do not eat, drink, or smoke during work.  Rinse mouth. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Collect leaking liquid in sealable containers. Wash away remainder with plenty of water.   
EC Classification
 
UN Classification
 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H0; F1; R0.  See Chemical Dangers. Dry. Well closed. Ventilation along the floor. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS ODOURLESS HYGROSCOPIC VISCOUS LIQUID. 

Physical dangers
The vapour is heavier than air. 

Chemical dangers
Reacts with strong oxidants. This generates fire hazard. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):. 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion. 

Inhalation risk
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 188.2°C
Melting point: -59°C
Relative density (water = 1): 1.04
Solubility in water: miscible
Vapour pressure, Pa at 20°C: 10.6
Relative vapour density (air = 1): 2.6
Flash point: 99°C c.c., 107°C o.c.
Auto-ignition temperature: 371°C
Explosive limits, vol% in air: 2.6-12.6
Octanol/water partition coefficient as log Pow: -0.92  
 

NOTES
Card has been partially updated in July 2007: see Occupational Exposure Limits. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       PROPYLENE GLYCOL (JECFA Evaluation)
       Propylene glycol (PIM 443)
       Propylene glycol (SIDS)