IPCS INCHEM Home
HALOTHANE
ICSC: 0277
Peer-Review Status: 27.11.2003 Validated
2-Bromo-2-chloro-1,1,1-trifluoroethane
1-Bromo-1-chloro-2,2,2-trifluoroethane 
CAS #: 151-67-7 RTECS #: KH6550000
EINECS #: 205-796-5
    Formula: BrClHC2F3
Molecular mass: 197.4

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.    In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION     In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   STRICT HYGIENE! AVOID EXPOSURE OF (PREGNANT) WOMEN!   
Inhalation Confusion. Dizziness. Drowsiness. Nausea. Unconciousness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Dry skin. Roughness.  Protective gloves.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness. Pain.  Wear safety goggles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: self-contained breathing apparatus. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.   
EC Classification
 
UN Classification
 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
  Keep in the dark. Ventilation along the floor. 

IMPORTANT DATA
Physical State; Appearance
HIGHLY VOLATILE COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air. 

Chemical dangers
Decomposes on heating. This produces toxic and corrosive fumes including hydrogen bromide, hydrogen chloride and hydrogen fluoride. Decomposes under the influence of light. 

Occupational exposure limits
MAK: 5 ppm, 41 mg/m³; Peak limitation category: II(8); Pregnancy risk group: B; (DFG 2002). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes. The substance may cause effects on the central nervous system and cardiovascular system. Exposure at high levels could cause unconsciousness. 

Effects of long-term or repeated exposure
The liquid defats the skin. The substance may have effects on the liver. This may result in liver impairment. Animal tests show that this substance possibly causes toxicity to human reproduction or development. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 50°C
Melting point: -118°C
Relative density (water = 1): 1.87
Solubility in water, g/100ml: 0.45
Vapour pressure, kPa at 20°C: 32.4
Relative vapour density (air = 1): 2.87
Relative density of the vapour/air-mixture at 20°C (air = 1): 2.9
Octanol/water partition coefficient as log Pow: 2.30  
 

NOTES
0.01% Thymol is used as a stabilizer.
Fluothane is a trade name.
High concentrations in the air cause a deficiency of oxygen with the risk of unconsciousness or death.
Check oxygen content before entering area. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations