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ETHYLENE GLYCOL
ICSC: 0270
Peer-Review Status: 25.03.1999 Validated
1,2-Ethanediol
1,2-Dihydroxyethane 
CAS #: 107-21-1 RTECS #: KW2975000
EC #: 603-027-00-1
EINECS #: 203-473-3
    Formula: HOCH2CH2OH
Molecular mass: 62.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible.  NO open flames.  Use water spray, powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION      
 
EXPOSURE   PREVENT GENERATION OF MISTS!   
Inhalation Cough. Dizziness. Headache.  Use ventilation.  Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. 
Skin Dry skin.  Protective gloves.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness. Pain.  Wear safety goggles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Dullness. Nausea. Unconsciousness. Vomiting.  Do not eat, drink, or smoke during work.  Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in sealable containers as far as possible. Wash away remainder with plenty of water.   
EC Classification
Symbol: Xn; R: 22; S: (2) 
UN Classification
 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H1; F1; R0.  Separated from strong oxidants and strong bases. Dry. Ventilation along the floor. 

IMPORTANT DATA
Physical State; Appearance
ODOURLESS COLOURLESS VISCOUS HYGROSCOPIC LIQUID. 

Physical dangers
 

Chemical dangers
On combustion, forms toxic gases. Reacts with strong oxidants and strong bases. 

Occupational exposure limits
TLV: 100mg/m³ (ceiling value); A4 (not classifiable as a human carcinogen); (ACGIH 2004).
MAK: 10 ppm, 26 mg/m³; Peak limitation category: I(2); Pregnancy risk group: C; Skin absorption (H); (DFG 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation and through the skin. 

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes and respiratory tract. The substance may cause effects on the kidneys and central nervous system. This may result in renal failure and brain injury. Exposure could cause lowering of consciousness. 

Effects of long-term or repeated exposure
The substance may have effects on the central nervous system. This may result in abnormal eye movements (nystagmus). 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 198°C
Melting point: -13°C
Relative density (water = 1): 1.1
Solubility in water: miscible
Vapour pressure, Pa at 20°C: 7
Relative vapour density (air = 1): 2.1
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 111°C c.c.
Auto-ignition temperature: 398°C
Explosive limits, vol% in air: 3.2-15.3
Octanol/water partition coefficient as log Pow: -1.93  
 

NOTES
The occupational exposure limit value should not be exceeded during any part of the working exposure.
Card has been partly updated in October 2005.
See sections Occupational Exposure Limits, Emergency Response. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Ethylene glycol (PIM 227)
       Ethylene glycol (PIM 227F, French)