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BENZIDINE
ICSC: 0224
Peer-Review Status: 24.11.2009 Validated
(1,1'-Biphenyl)-4,4'-diamine
4,4'-Diaminobiphenyl
p-Diaminodiphenyl
Biphenyl-4,4'-ylenediamine 
CAS #: 92-87-5 RTECS #: DC9625000
UN #: 1885
EC #: 612-042-00-2
EINECS #: 202-199-1
    Formula: C12H12N2 / NH2C6H4-C6H4NH2
Molecular mass: 184.2

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, foam, powder, carbon dioxide. 
EXPLOSION      
 
EXPOSURE See EFFECTS OF LONG-TERM OR REPEATED EXPOSURE.  AVOID ALL CONTACT!   
Inhalation   Use closed system and ventilation.  Fresh air, rest. 
Skin MAY BE ABSORBED!  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Wear protective gloves when administering first aid. 
Eyes   Wear face shield or eye protection in combination with breathing protection if powder.  Rinse with plenty of water (remove contact lenses if easily possible). 
Ingestion   Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.  Unbreakable packaging.
Put breakable packaging into closed unbreakable container.
Do not transport with food and feedstuffs. 
EC Classification
Symbol: T, N; R: 45-22-50/53; S: 53-45-60-61; Note: E 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 
GHS Classification
Signal: Danger
Harmful if swallowed
Suspected of causing genetic defects
May cause cancer
Very toxic to aquatic life with long lasting effects 
excl mark;warncancer;health hazenviro;aqua

EMERGENCY RESPONSE SAFE STORAGE
  Provision to contain effluent from fire extinguishing. Separated from strong oxidants and food and feedstuffs. Keep in the dark. Well closed. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS OR REDDISH CRYSTALLINE POWDER. TURNS DARK ON EXPOSURE TO AIR AND LIGHT. 

Physical dangers
No data. 

Chemical dangers
Decomposes on heating and on burning. This produces toxic fumes including nitrogen oxides. Reacts violently with strong oxidants; especially nitric acid. 

Occupational exposure limits
TLV: (skin); A1 (confirmed human carcinogen); (ACGIH 2009).
MAK: Carcinogen category: 1; Skin absorption (H); (DFG 2009). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered. 

Effects of short-term exposure
 

Effects of long-term or repeated exposure
This substance is carcinogenic to humans. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 401°C
Melting point: 120°C
Density: 1.3 g/cm³
Solubility in water, g/100ml at 25°C: <0.05 (very poor)
Relative vapour density (air = 1): 6.4
Octanol/water partition coefficient as log Pow: 1.34  
The substance is very toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment. 

NOTES
Do NOT take working clothes home. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Benzidine  (IARC Summary & Evaluation, Supplement7, 1987)
       Benzidine (IARC Summary & Evaluation, Volume 1, 1972)