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ACETIC ANHYDRIDEICSC: 0209
April 2006
CAS #: 108-24-7Acetic acid, anhydride
Acetic oxide
Ethanoic anhydride
Acetyl oxide
UN #: 1715
EINECS #: 203-564-8

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Flammable.  Above 49°C explosive vapour/air mixtures may be formed.  NO open flames, NO sparks and NO smoking.  Above 49°C use a closed system, ventilation and explosion-proof electrical equipment.  Use alcohol-resistant foam, powder, carbon dioxide. See Notes.  In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water. 

 AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR! 
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation Cough. Laboured breathing. Shortness of breath. Sore throat.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. 
Skin Redness. Skin burns. Pain. Blisters. Symptoms may be delayed.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Watering of the eyes. Redness. Pain. Burns.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Burning sensation. Shock or collapse.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Consult an expert! Personal protection: chemical protection suit, face shield and filter respirator for acid gases and vapours adapted to the airborne concentration of the substance. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

flam;flameexcl mark;warncorr
DANGER
Flammable liquid and vapour
Harmful if swallowed
Causes severe skin burns and eye damage 

Transportation
UN Classification
UN Hazard Class: 8; UN Subsidiary Risks: 3; UN Pack Group: II 

STORAGE
Fireproof. Separated from food and feedstuffs and incompatible materials. See Chemical Dangers. Dry. 
PACKAGING
Do not transport with food and feedstuffs. 
ACETIC ANHYDRIDE ICSC: 0209
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID WITH PUNGENT ODOUR. 

Physical dangers
 

Chemical dangers
Decomposes on burning. This produces toxic gases and toxic fumes including acetic acid fumes. Reacts violently with alcohols, amines, oxidants, strong bases and water. Attacks many metals in the presence of water or when dry. 

Formula: C4H6O3/(CH3CO)2O
Molecular mass: 102.1
Boiling point: 139°C
Melting point: -73°C
Relative density (water = 1): 1.08
Solubility in water: reaction
Vapour pressure, kPa at 20°C: 0.5
Relative vapour density (air = 1): 3.5
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.01
Flash point: 49°C c.c.
Auto-ignition temperature: 316°C
Explosive limits, vol% in air: 2.7-10.3
Octanol/water partition coefficient as log Pow: -0.27  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion. 

Effects of short-term exposure
Lachrymation. The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation may cause asthma-like reactions. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of long-term or repeated exposure
Inhalation may cause asthma-like reactions (RADS). 


Occupational exposure limits
MAK: 21 mg/m3, 5 ppm; pregnancy risk group: D.
TLV: 1 ppm as TWA; 3 ppm as STEL; A4 (not classifiable as a human carcinogen) 

ENVIRONMENT
 

NOTES
Forms acetic acid when mixed with water.
Major fires must be extinguished with large amounts of water from a distance. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: C; R: 10-20/22-34; S: (1/2)-26-36/37/39-45 

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    See Also:
       Toxicological Abbreviations
       Acetic anhydride (SIDS)