IPCS INCHEM Home
TRIMETHYLAMINE
(cylinder)
ICSC: 0206
Peer-Review Status: 10.10.2002 Validated
N,N-Dimethylmethanamine
TMA 
CAS #: 75-50-3 RTECS #: PA0350000
UN #: 1083 (anhydrous)
EC #: 612-001-00-9
EINECS #: 200-875-0
    Formula: C3H9N / (CH3)3N
Molecular mass: 59.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Extremely flammable. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking.  Shut off supply; if not possible and no risk to surroundings, let the fire burn itself out. In other cases extinguish with powder, carbon dioxide. 
EXPLOSION Gas/air mixtures are explosive.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Use non-sparking handtools.  In case of fire: keep cylinder cool by spraying with water. Combat fire from a sheltered position. 
 
EXPOSURE   STRICT HYGIENE!   
Inhalation Burning sensation. Cough. Headache. Sore throat. Laboured breathing. Shortness of breath. Symptoms may be delayed. See Notes.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. 
Skin ON CONTACT WITH LIQUID: FROSTBITE.  Cold-insulating gloves. Protective clothing.  ON FROSTBITE: rinse with plenty of water, do NOT remove clothes. Refer for medical attention . 
Eyes Redness. Pain. Blurred vision.  Wear safety goggles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion   Do not eat, drink, or smoke during work.   

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Ventilation. Remove all ignition sources. NEVER direct water jet on liquid. Remove vapour with fine water spray.   
EC Classification
Symbol: F+, Xn; R: 12-20-37/38-41; S: (2)-16-26-39 
UN Classification
UN Hazard Class: 2.1 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-20S1083.
NFPA Code: H3; F4; R0. 
Fireproof. Cool. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS COMPRESSED LIQUEFIED GAS WITH CHARACTERISTIC ODOUR. 

Physical dangers
The gas is heavier than air and may travel along the ground; distant ignition possible. 

Chemical dangers
Decomposes on burning. This produces toxic fumes including nitrogen oxides. The solution in water is a strong base. It reacts violently with acid and is corrosive. Reacts violently with oxidants and ethylene oxide. Attacks metals such as copper, zinc, aluminium, tin and their alloys. 

Occupational exposure limits
TLV: 5 ppm as TWA; 15 ppm as STEL; (ACGIH 2002).
MAK: 2 ppm, 4.9 mg/m³; Peak limitation category: I(2); Pregnancy risk group: C; (DFG 2006). 

Routes of exposure
The substance can be absorbed into the body by inhalation. 

Inhalation risk
A harmful concentration of this gas in the air will be reached very quickly on loss of containment. 

Effects of short-term exposure
The substance is severely irritating to the eyes and respiratory tract. Rapid evaporation of the liquid may cause frostbite. Inhalation may cause lung oedema. See Notes. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 3°C
Melting point: -117°C
Relative density (water = 1): 0.6 (liquid)
Solubility in water: very good
Vapour pressure, kPa at 20°C: 187
Relative vapour density (air = 1): 2
Flash point: Flammable gas
Auto-ignition temperature: 190°C
Explosive limits, vol% in air: 2.0-11.6
Octanol/water partition coefficient as log Pow: 0.2  
 

NOTES
Turn leaking cylinder with the leak up to prevent escape of gas in liquid state.
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation is therefore essential.
Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered.
Card has been partly updated in October 2006: see sections Occupational Exposure Limits. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       TRIMETHYLAMINE (JECFA Evaluation)