IPCS INCHEM Home
NITROGLYCERIN
ICSC: 0186
Peer-Review Status: 20.10.2005 Validated
Glyceryl trinitrate
Glycerol trinitrate
1,2,3-Propanetriol trinitrate
Blasting oil 
CAS #: 55-63-0 RTECS #: QX2100000
UN #: 0143 (desensitized)
EC #: 603-034-00-X
EINECS #: 200-240-8
    Formula: C3H5N3O9 / C3H5(NO3)3
Molecular mass: 227.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Many reactions may cause fire or explosion. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking. NO contact with hot surfaces.  Use water spray, powder, foam, carbon dioxide. 
EXPLOSION Risk of fire and explosion. Explosive.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Use non-sparking handtools. Do NOT expose to friction or shock.  In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position. 
 
EXPOSURE   STRICT HYGIENE!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Headache. Flushing of the face. Dizziness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Flushing of the face. Headache. Dizziness. Nausea. Vomiting. Shock or collapse.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Give a slurry of activated charcoal in water to drink. Refer immediately for medical attention. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Remove all ignition sources. Do NOT wash away into sewer. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: E, T+, N; R: 3-26/27/28-33-51/53; S: (1/2)-33-35-36/37-45-61 
UN Classification
UN Hazard Class: 1.1D (Desensitized); UN Subsidiary Risks: 6.1 (Desensitized) 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-10G1.
NFPA Code: H2; F3; R4. 
Store only if stabilized. Store in an area without drain or sewer access. Fireproof. Well closed. Separated from food and feedstuffs. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS-TO-YELLOW VISCOUS LIQUID OR PALE YELLOW CRYSTALS. 

Physical dangers
 

Chemical dangers
Heating may cause violent combustion or explosion. May decompose explosively on shock, friction or concussion. On combustion, forms toxic fumes including nitrogen oxides. Reacts with ozone. This generates explosion hazard. 

Occupational exposure limits
TLV: 0.05ppm as TWA; (skin); (ACGIH 2005).
MAK: Carcinogen category: 3B; Skin absorption (H); BAT issued; (DFG 2005). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. 

Effects of short-term exposure
The substance is irritating to the eyes. The substance may cause effects on the cardiovascular system. This may result in lowering of blood pressure. Medical observation is indicated. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. Repeated exposure leads to marked tolerance and short absence from exposure may lead to sudden death. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Decomposes at 218°C
Melting point: 13°C
Relative density (water = 1): 1.6
Solubility in water: poor
Vapour pressure, Pa at 20°C: 0.03
Relative vapour density (air = 1): 7.8
Auto-ignition temperature: 270°C
Octanol/water partition coefficient as log Pow: 1.62  
The substance is toxic to aquatic organisms. 

NOTES
Combustion in a confined space may turn into detonation.
Use of alcoholic beverages enhances the harmful effect.
Other UN numbers are: UN 0144 Nitroglycerin, solution in alcohol with more than 1% but not more than 10% nitroglycerin; UN Haz Class 1.1D.
UN 1204 Nitroglycerin, solution in alcohol with not more than 1% of nitroglycerin; UN Haz Class 3, Pack Group II.
UN 3064 Nitroglycerin, solution in alcohol with more than 1% but not more than 5% of nitroglycerin, UN Haz Class 3, Pack Group II.
An added stabilizer or inhibitor can influence the toxicological properties of this substance, consult an expert. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations