ICSC 0091 - ACRYLAMIDE

ACRYLAMIDE

ICSC: 0091
_{Peer-Review Status: 04.10.2000 Validated}

2-Propene amide
Acrylic acid amide
Vinyl amide

CAS #: 79-06-1 RTECS #: AS3325000
UN #: 2074
EC #: 616-003-00-0
EINECS #: 201-173-7

Formula: C₃H₅NO / CH₂=CHCONH₂
Molecular mass: 71.1

TYPES OF HAZARD / EXPOSURE	ACUTE HAZARDS / SYMPTOMS	PREVENTION	FIRST AID / FIRE FIGHTING
FIRE	Combustible. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Use water spray, powder, alcohol-resistant foam, carbon dioxide.
EXPLOSION	Finely dispersed particles form explosive mixtures in air.	Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent deposition of dust.

EXPOSURE		PREVENT DISPERSION OF DUST! AVOID ALL CONTACT!	IN ALL CASES CONSULT A DOCTOR!
Inhalation	Cough. Sore throat. Weakness.	Use local exhaust or breathing protection.	Fresh air, rest. Refer for medical attention.
Skin	MAY BE ABSORBED! Redness. Pain. Further see Inhalation.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .
Eyes	Redness. Pain.	Wear face shield or eye protection in combination with breathing protection.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Abdominal pain. Weakness.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Give one or two glasses of water to drink. Refer for medical attention .

SPILLAGE DISPOSAL	PACKAGING & LABELLING
Consult an expert! Personal protection: chemical protection suit including self-contained breathing apparatus. Sweep spilled substance into covered containers. Carefully collect remainder. Then store and dispose of according to local regulations.	Special material. EC Classification Symbol: T; R: 45-46-20/21-25-36/38-43-48/23/24/25-62; S: 53-45; Note: D, E UN Classification UN Hazard Class: 6.1; UN Pack Group: III GHS Classification

EMERGENCY RESPONSE	SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT2-III. NFPA Code: H3; F2; R2.	Separated from oxidants. Cool. Keep in the dark. Well closed.

IMPORTANT DATA

Physical State; Appearance
WHITE CRYSTALS.

Physical dangers

Chemical dangers
The substance polymerizes violently due to heating above 85°C or under the influence of light and oxidants.

Occupational exposure limits
TLV: 0.03mg/m³ as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2004).
MAK: Carcinogen category: 2; Germ cell mutagen group: 2; Skin absorption (H); (DFG 2004).

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly.

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system.

Effects of long-term or repeated exposure
The substance may have effects on the nervous system. This may result in peripheral nerve damage. This substance is probably carcinogenic to humans. May cause heritable genetic damage to human germ cells.

PHYSICAL PROPERTIES	ENVIRONMENTAL DATA
Melting point: 84.5°C Density: 1.13 g/cm³ Solubility in water, g/100ml at 25°C: 204 Vapour pressure, Pa at 20°C: 1 Relative vapour density (air = 1): 2.45 Flash point: 138°C c.c. Auto-ignition temperature: 424°C Octanol/water partition coefficient as log Pow: -1.65/-0.67	This substance may be hazardous to the environment. Special attention should be given to fish.

NOTES

Depending on the degree of exposure, periodic medical examination is suggested.
Do NOT take working clothes home.
Card has been partly updated in October 2004.
See sections Occupational Exposure Limits, EU classification, Emergency Response.

ADDITIONAL INFORMATION

IPCS
International
Programme on
Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012

LEGAL NOTICE

Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.

    See Also:
       Toxicological Abbreviations
       Acrylamide (EHC 49, 1985)
       Acrylamide (HSG 45, 1991)
       Acrylamide (WHO Food Additives Series 55)
       ACRYLAMIDE (JECFA Evaluation)
       Acrylamide (PIM 652)
       Acrylamide (IARC Summary & Evaluation, Volume 60, 1994)