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NITROUS OXIDE
(cylinder)
ICSC: 0067
Peer-Review Status: 05.08.2003 Validated
Dinitrogen monoxide
Hyponitrous acid anhydride
Laughing gas
Dinitrogen oxide 
CAS #: 10024-97-2 RTECS #: QX1350000
UN #: 1070 (compressed)
EINECS #: 233-032-0
    Formula: N2O
Molecular mass: 44.0

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Not combustible but enhances combustion of other substances. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking.  In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION See Chemical Dangers. Risk of fire and explosion.  Closed system, ventilation, explosion-proof electrical equipment and lighting.  In case of fire: keep cylinder cool by spraying with water. Combat fire from a sheltered position. 
 
EXPOSURE   AVOID EXPOSURE OF (PREGNANT) WOMEN!   
Inhalation Euphoria. Drowsiness. Unconciousness.  Use ventilation. Use local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin ON CONTACT WITH LIQUID: FROSTBITE.  Cold-insulating gloves.  ON FROSTBITE: rinse with plenty of water, do NOT remove clothes. Refer for medical attention . 
Eyes ON CONTACT WITH LIQUID: FROSTBITE.  Wear safety goggles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion   Do not eat, drink, or smoke during work.   

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Personal protection: self-contained breathing apparatus. Ventilation. NEVER direct water jet on liquid. If liquid: do NOT absorb in saw-dust or other combustible components.   
EC Classification
 
UN Classification
UN Hazard Class: 2.2; UN Subsidiary Risks: 5.1 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-20S1070.  Fireproof if in building. Separated from incompatible materials. See Chemical Dangers. Cool. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS COMPRESSED LIQUEFIED GAS WITH CHARACTERISTIC ODOUR. 

Physical dangers
The gas is heavier than air and may accumulate in lowered spaces causing a deficiency of oxygen. 

Chemical dangers
Reacts violently with sulphurous anhydride, amorphous boron, phosphine, ethers, aluminium, hydrazine, phenyl-lithium and tungsten carbide. This generates fire and explosion hazard. The substance is a strong oxidant above 300°C. Mixtures with ammonia, carbon monoxide, hydrogen sulfide, oil, grease and fuels are explosive. 

Occupational exposure limits
TLV: 50ppm as TWA; A4 (not classifiable as a human carcinogen); (ACGIH 2004).
MAK: 100 ppm, 180 mg/m³; Peak limitation category: II(2); Pregnancy risk group: C; (DFG 2006). 

Routes of exposure
The substance can be absorbed into the body by inhalation. 

Inhalation risk
A harmful concentration of this gas in the air will be reached very quickly on loss of containment. 

Effects of short-term exposure
The liquid may cause frostbite. The substance may cause effects on the central nervous system. This may result in lowering of consciousness. 

Effects of long-term or repeated exposure
The substance may have effects on the bone marrow and peripheral nervous system. May cause reproductive toxicity in humans. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: -88.5°C
Melting point: -90.8°C
Relative density (water = 1): 1.23 (-89°C)
Solubility in water, g/100ml at 15°C: 0.15
Vapour pressure, kPa at 20°C: 5150
Relative vapour density (air = 1): 1.53
Octanol/water partition coefficient as log Pow: 0.35  
 

NOTES
Turn leaking cylinder with the leak up to prevent escape of gas in liquid state.
Other UN number: 2201 Nitrous oxide, refrigerated liquid.
Card has been partly updated in April 2005.
See section Occupational Exposure Limits. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.
    See Also:
       Toxicological Abbreviations
       NITROUS OXIDE (JECFA Evaluation)
       Nitrous oxide (PIM 381)