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p-NITROPHENOLICSC: 0066
4-Nitrophenol
4-Hydroxynitrobenzene
November 1998
CAS #: 100-02-7
UN #: 1663
EC Number: 202-811-7

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  Finely dispersed particles form explosive mixtures in air.  NO open flames.  Closed system, dust explosion-proof electrical equipment and lighting. Prevent deposition of dust.  Use water spray, powder, foam, carbon dioxide.  In case of fire: keep drums, etc., cool by spraying with water. 

 PREVENT DISPERSION OF DUST! STRICT HYGIENE!  
  SYMPTOMS PREVENTION FIRST AID
Inhalation Blue lips, fingernails and skin. Cough. Burning sensation. Confusion. Convulsions. Dizziness. Headache. Nausea. Sore throat. Unconsciousness. Weakness.  Use local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness. Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain.  Wear safety spectacles, face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Sore throat. Vomiting. See Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Rest. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

 

Transportation
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 

STORAGE
Separated from combustible substances, reducing agents and food and feedstuffs. Well closed. 
PACKAGING
Do not transport with food and feedstuffs. 
p-NITROPHENOL ICSC: 0066
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS-TO-PALE-YELLOW CRYSTALS. 

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air. 

Chemical dangers
May explode on heating. Decomposes on heating. This produces toxic fumes including nitrogen oxides. Mixtures with potassium hydroxide are explosive. 

Formula: C6H5NO3
Molecular mass: 139.1
Decomposes at 279°C
Melting point: 111-116°C
Density: 1.5 g/cm³
Solubility in water, g/100ml at 20°C: 1.24
Vapour pressure, Pa at 20°C: 0.0032
Flash point: 169°C
Auto-ignition temperature: 490°C
Octanol/water partition coefficient as log Pow: 1.91  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. 


OCCUPATIONAL EXPOSURE LIMITS
 

ENVIRONMENT
The substance is toxic to aquatic organisms. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: Xn; R: 20/21/22-33; S: (2)-28 

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    See Also:
       Toxicological Abbreviations