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CHLORODIFLUOROMETHANEICSC: 0049
July 2002
CAS #: 75-45-6Monochlorodifluoromethane
Methane, chlorodifluoro-
HCFC 22
R 22
UN #: 1018
EINECS #: 200-871-9

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible under specific conditions. Gives off irritating or toxic fumes (or gases) in a fire.    NO open flames.    In case of fire in the surroundings, use appropriate extinguishing media.  In case of fire: keep cylinder cool by spraying with water. 

   
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation Irregular heartbeat. Confusion. Drowsiness. Unconsciousness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. 
Skin ON CONTACT WITH LIQUID: FROSTBITE.  Cold-insulating gloves.  ON FROSTBITE: rinse with plenty of water, do NOT remove clothes. Refer for medical attention . 
Eyes Redness. Pain.  Wear safety goggles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion   Do not eat, drink, or smoke during work.   

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Ventilation. 

According to UN GHS Criteria

 

Transportation
UN Classification
UN Hazard Class: 2.2 

STORAGE
Fireproof. Cool. Ventilation along the floor. 
PACKAGING
Special insulated cylinder. 
CHLORODIFLUOROMETHANE ICSC: 0049
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS COMPRESSED LIQUEFIED GAS. 

Physical dangers
The gas is heavier than air and may accumulate in lowered spaces causing a deficiency of oxygen. 

Chemical dangers
Decomposes on contact with hot surfaces or flames. This produces toxic and corrosive gases including hydrogen chloride (see ICSC 0163), phosgene (see ICSC 0007), hydrogen fluoride (See ICSC 0283) and carbonyl fluoride (See ICSC 0633). Attacks magnesium and its alloys. 

Formula: CHClF2
Molecular mass: 86.5
Boiling point: -41°C
Melting point: -146°C
Relative density (water = 1): 1.21
Solubility in water, g/100ml at 25°C: 0.3
Vapour pressure, kPa at 20°C: 908
Relative vapour density (air = 1): 3.0
Auto-ignition temperature: 632°C
Octanol/water partition coefficient as log Pow: 1.08  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation. 

Effects of short-term exposure
Rapid evaporation of the liquid may cause frostbite. The substance may cause effects on the cardiovascular system and central nervous system. This may result in cardiac disorders and central nervous system depression. Exposure could cause lowering of consciousness. See Notes. 

Inhalation risk
On loss of containment this substance can cause suffocation by lowering the oxygen content of the air in confined areas. 

Effects of long-term or repeated exposure
 


Occupational exposure limits
TLV: 1000 ppm as TWA; A4 (not classifiable as a human carcinogen).
MAK: 1800 mg/m3, 500 ppm; peak limitation category: II(8); pregnancy risk group: C.
EU-OEL: 3600 mg/m3, 1000 ppm as TWA 

ENVIRONMENT
This substance may be hazardous to the environment. Special attention should be given to its impact on the ozone layer. 

NOTES
High concentrations in the air cause a deficiency of oxygen with the risk of unconsciousness or death.
Check oxygen content before entering the area.
The odour warning when the exposure limit value is exceeded is insufficient.
Do NOT use in the vicinity of a fire or a hot surface, or during welding.
Turn leaking cylinder with the leak up to prevent escape of gas in liquid state. 

ADDITIONAL INFORMATION
  EC Classification
 

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    See Also:
       Toxicological Abbreviations
       Chlorodifluoromethane  (IARC Summary & Evaluation, Supplement7, 1987)
       Chlorodifluoromethane  (IARC Summary & Evaluation, Volume 41, 1986)
       Chlorodifluoromethane  (IARC Summary & Evaluation, Volume 71, 1999)