IPCS INCHEM Home
CHLORODIFLUOROMETHANE
(cylinder)
ICSC: 0049
Peer-Review Status: 03.07.2002 Validated
Monochlorodifluoromethane
Methane, chlorodifluoro-
HCFC 22
R 22 
CAS #: 75-45-6 RTECS #: PA6390000
UN #: 1018
EINECS #: 200-871-9
    Formula: CHClF2
Molecular mass: 86.5

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible under specific conditions. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION     In case of fire: keep cylinder cool by spraying with water. 
 
EXPOSURE      
Inhalation Irregular heartbeat. Confusion. Drowsiness. Unconciousness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. 
Skin ON CONTACT WITH LIQUID: FROSTBITE.  Cold-insulating gloves.  ON FROSTBITE: rinse with plenty of water, do NOT remove clothes. Refer for medical attention . 
Eyes Redness. Pain.  Wear safety goggles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion   Do not eat, drink, or smoke during work.   

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Ventilation.  Special insulated cylinder. 
EC Classification
 
UN Classification
UN Hazard Class: 2.2 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-20G2A.  Fireproof. Cool. Ventilation along the floor. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS COMPRESSED LIQUEFIED GAS. 

Physical dangers
The gas is heavier than air and may accumulate in lowered spaces causing a deficiency of oxygen. 

Chemical dangers
Decomposes on contact with hot surfaces or flames. This produces toxic and corrosive gases including hydrogen chloride (see ICSC 0163), phosgene (see ICSC 0007), hydrogen fluoride (See ICSC 0283) and carbonyl fluoride (See ICSC 0633). Attacks magnesium and its alloys. 

Occupational exposure limits
TLV: 1000ppm as TWA; A4 (not classifiable as a human carcinogen); (ACGIH 2001).
MAK: 500 ppm, 1800 mg/m³; Peak limitation category: II(8); Pregnancy risk group: C; (DFG 2006). 

Routes of exposure
The substance can be absorbed into the body by inhalation. 

Inhalation risk
On loss of containment this substance can cause suffocation by lowering the oxygen content of the air in confined areas. 

Effects of short-term exposure
Rapid evaporation of the liquid may cause frostbite. The substance may cause effects on the cardiovascular system and central nervous system. This may result in cardiac disorders and central nervous system depression. Exposure could cause lowering of consciousness. See Notes. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: -41°C
Melting point: -146°C
Relative density (water = 1): 1.21
Solubility in water, g/100ml at 25°C: 0.3
Vapour pressure, kPa at 20°C: 908
Relative vapour density (air = 1): 3.0
Auto-ignition temperature: 632°C
Octanol/water partition coefficient as log Pow: 1.08  
This substance may be hazardous to the environment. Special attention should be given to its impact on the ozone layer. 

NOTES
High concentrations in the air cause a deficiency of oxygen with the risk of unconsciousness or death.
Check oxygen content before entering area.
The odour warning when the exposure limit value is exceeded is insufficient.
Do NOT use in the vicinity of a fire or a hot surface, or during welding.
Turn leaking cylinder with the leak up to prevent escape of gas in liquid state.
Freon 22, Frigen 22, Halon 22 are trade names.
Card has been partially updated in July 2007: see Occupational Exposure Limits. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.
    See Also:
       Toxicological Abbreviations
       Chlorodifluoromethane  (IARC Summary & Evaluation, Supplement7, 1987)
       Chlorodifluoromethane  (IARC Summary & Evaluation, Volume 41, 1986)
       Chlorodifluoromethane  (IARC Summary & Evaluation, Volume 71, 1999)