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1,4-DICHLOROBENZENE
ICSC: 0037
Peer-Review Status: 26.11.2003 Validated
p-Dichlorobenzene
PDCB 
CAS #: 106-46-7 RTECS #: CZ4550000
UN #: 3077
EC #: 602-035-00-2
EINECS #: 203-400-5
    Formula: C6H4Cl2
Molecular mass: 147

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, powder, foam, carbon dioxide. 
EXPLOSION Above 66°C explosive vapour/air mixtures may be formed.  Above 66°C use a closed system, ventilation and explosion-proof electrical equipment.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   AVOID ALL CONTACT!   
Inhalation Burning sensation. Cough. Drowsiness. Headache. Nausea. Shortness of breath. Vomiting.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin   Protective gloves.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes Redness. Pain.  Wear safety goggles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Diarrhoea. Further see Inhalation.  Do not eat, drink, or smoke during work.  Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs.
Marine pollutant. 
EC Classification
Symbol: Xn, N; R: 36-40-50/53; S: (2)-36/37-46-60-61 
UN Classification
UN Hazard Class: 9; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-90GM7-III.
NFPA Code: H2; F2; R0. 
Provision to contain effluent from fire extinguishing. Separated from strong oxidants and food and feedstuffs. Keep in a well-ventilated room. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS-TO-WHITE CRYSTALS WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
On combustion, forms toxic and corrosive fumes including hydrogen chloride. Reacts with strong oxidants. 

Occupational exposure limits
TLV: 10ppm as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2004).
MAK: Carcinogen category: 2; Germ cell mutagen group: 3B; Skin absorption (H); (DFG 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation and by ingestion. 

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes and respiratory tract. The substance may cause effects on the blood. This may result in haemolytic anaemia. The substance may cause effects on the central nervous system. Medical observation is indicated. 

Effects of long-term or repeated exposure
The substance may have effects on the liver, kidneys and blood. This substance is possibly carcinogenic to humans. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 174°C
Melting point: 53°C
Density: 1.2 g/cm³
Solubility in water, mg/l at 25°C: 80
Vapour pressure, Pa at 20°C: 170
Relative vapour density (air = 1): 5.08
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.01
Flash point: 66°C c.c.
Explosive limits, vol% in air: 6.2-16
Octanol/water partition coefficient as log Pow: 3.37  
The substance is toxic to aquatic organisms. Bioaccumulation of this chemical may occur in fish. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Do NOT take working clothes home.
Card has been partly updated in October 2004.
See sections Occupational Exposure Limits, EU classification, Emergency Response. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.
    See Also:
       Toxicological Abbreviations