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o-CRESOL
ICSC: 0030
Peer-Review Status: 13.11.2008 Validated
2-Hydroxy-1-methylbenzene
2-Methylphenol
ortho-Hydroxytoluene
2-Cresol 
CAS #: 95-48-7 RTECS #: GO6300000
UN #: 3455
EC #: 604-004-00-9
EINECS #: 202-423-8
    Formula: C7H8O / CH3C6H4OH
Molecular mass: 108.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, foam, powder, carbon dioxide. 
EXPLOSION Above 81°C explosive vapour/air mixtures may be formed.  Above 81°C use a closed system and ventilation.   
 
EXPOSURE   AVOID ALL CONTACT!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Cough. Sore throat. Burning sensation. Headache. Nausea. Vomiting. Shortness of breath. Laboured breathing.  Use local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer immediately for medical attention. 
Skin MAY BE ABSORBED! Redness. Pain. Blisters. Skin burns.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer immediately for medical attention. 
Eyes Redness. Pain. Severe deep burns.  Wear face shield or eye protection in combination with breathing protection.  Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer immediately for medical attention. 
Ingestion Burns in mouth and throat. Burning sensation in the throat and chest. Nausea. Vomiting. Abdominal pain. Shock or collapse.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Do NOT induce vomiting. Refer immediately for medical attention. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: chemical protection suit and filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs.
Marine pollutant. 
EC Classification
Symbol: T, C; R: 24/25-34; S: (1/2)-36/37/39-45; Note: C 
UN Classification
UN Hazard Class: 6.1; UN Subsidiary Risks: 8; UN Pack Group: II 
GHS Classification
Signal: Danger
Toxic if swallowed
Toxic in contact with skin
Causes severe skin burns and eye damage
Causes damage to central nervous system and blood
Causes damage to through prolonged or repeated exposure
Toxic to aquatic life 
corrskull;toxiccancer;health haz

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GTC2-II.
NFPA Code: H3; F2; R0. 
Separated from strong oxidants and food and feedstuffs. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS CRYSTALS WITH CHARACTERISTIC ODOUR. TURNS DARK ON EXPOSURE TO AIR AND LIGHT. 

Physical dangers
No data. 

Chemical dangers
Reacts violently with strong oxidants. The solution in water is a weak acid. 

Occupational exposure limits
TLV: 5ppm as TWA; (skin); (ACGIH 2008).
MAK: Carcinogen category: 3A; Skin absorption (H); BAT issued; (DFG 2008). 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. Serious by all routes of exposure. 

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation may cause lung oedema. The substance may cause effects on the central nervous system. This may result in lowering of consciousness. The substance may cause effects on the blood. This may result in destruction of blood cells. Exposure far above the OEL could cause death. Medical observation is indicated. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the nervous system. This may result in impaired functions. The substance may have effects on the blood. This may result in anaemia. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 191°C
Melting point: 31°C
Density: 1.05 g/cm³
Solubility in water, g/100ml at 25°C: 2.5 (moderate)
Vapour pressure, Pa at 25°C: 33
Relative vapour density (air = 1): 3.7
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 81°C c.c.
Auto-ignition temperature: 555°C
Explosive limits, vol% in air: 1.3-?
Octanol/water partition coefficient as log Pow: 1.95  
The substance is toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment. 

NOTES
 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.
    See Also:
       Toxicological Abbreviations
       o-CRESOL (JECFA Evaluation)
       o-Cresol  (SIDS)